CRS4C-2, characterized by its predicted protein homodimerization activity and involvement in responding to bacteria, emerges as a pivotal component in the host's defense against microbial threats. The activation of CRS4C-2 involves a complex interplay of various chemicals, acting as direct or indirect activators, influencing key pathways and processes in the immune response. One noteworthy activator, LL-37, directly engages in protein homodimerization, promoting an enhanced response to bacterial stimuli. CpG Oligodeoxynucleotides and Beta-Glucans act as potent activators, engaging immune receptors and amplifying CRS4C-2 activity to support effective host defense mechanisms, particularly within azurophil granules.
Resolvin E1 and Quercetin contribute to resolving inflammation and modulating immune responses, ultimately supporting an enhanced response to bacteria by upregulating CRS4C-2 activity. Lactoferrin and N-Acetylcysteine (NAC) operate in the extracellular space, promoting effective recognition and response to bacterial challenges, reinforcing the target's activity. Vitamin D, Polyphenols, Omega-3 Fatty Acids, Zinc, and Curcumin influence key pathways, leading to an upregulated activity of CRS4C-2, contributing to a robust defense against bacterial challenges, particularly within azurophil granules. In summary, the activation of CRS4C-2 involves a sophisticated interplay of various chemicals, collectively enhancing the response to bacteria and fortifying host defense mechanisms. Understanding these activation mechanisms provides insights into potential strategies for bolstering the innate immune response against bacterial challenges, highlighting the intricate dynamics of host-microbial interactions.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING | 
|---|---|---|---|---|---|---|
| Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
| Quercetin activates CRS4C-2 by modulating immune responses, enhancing the response to bacteria. This flavonoid influences key pathways, leading to an upregulated activity of the target and contributing to a more effective defense against bacterial challenges, particularly in extracellular spaces. | ||||||
| Lactoferrin | 146897-68-9 | sc-394420 sc-394420A sc-394420B sc-394420C | 10 mg 50 mg 100 mg 1 g | $120.00 $400.00 $569.00 $1465.00 | ||
| Lactoferrin activates CRS4C-2 by promoting an enhanced response to bacteria, especially in the extracellular space. This multifunctional glycoprotein supports the target's activity, contributing to an effective recognition and response to bacterial challenges, bolstering host defense mechanisms within azurophil granules. | ||||||
| N-Acetyl-L-cysteine | 616-91-1 | sc-202232 sc-202232A sc-202232C sc-202232B | 5 g 25 g 1 kg 100 g | $33.00 $73.00 $265.00 $112.00 | 34 | |
| N-Acetylcysteine activates CRS4C-2 by modulating oxidative stress, supporting an enhanced response to bacteria. This antioxidant reinforces the target's activity, providing a potential avenue to amplify the host defense against bacterial challenges, particularly within azurophil granules. | ||||||
| Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $70.00 $160.00 $290.00 | 2 | |
| Vitamin D (Cholecalciferol) activates CRS4C-2 by modulating immune responses, enhancing the response to bacteria. This fat-soluble vitamin influences key pathways, contributing to an upregulated activity of the target and supporting a more effective defense against bacterial challenges in the extracellular space. | ||||||
| Zinc | 7440-66-6 | sc-213177 | 100 g | $47.00 | ||
| Zinc activates CRS4C-2 by influencing immune signaling, promoting an enhanced response to bacteria. This essential trace element supports the target's activity, providing a potential avenue to amplify the host defense against bacterial challenges, particularly within azurophil granules. | ||||||
| Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
| Curcumin activates CRS4C-2 by modulating immune signaling, enhancing the response to bacteria. This polyphenol influences key pathways, contributing to an upregulated activity of the target and supporting a robust defense against bacterial challenges, particularly in extracellular spaces. | ||||||