Cnpy1 Inhibitors

Cnpy1 Inhibitors primarily encompasses molecules designed to modulate FGF signaling pathways, given Cnpy1's potential association with this pathway. These compounds target various nodes within the FGF pathway, especially at the level of FGFR kinases. For instance, SU5402, PD173074, and AZD4547 are potent inhibitors of FGF receptor tyrosine kinases. Their mechanism of action can largely be attributed to the inhibition of these kinases, resulting in the downstream modulation of FGF signaling.

Furthermore, chemicals like Dovitinib and Lenvatinib exhibit broader kinase inhibition profiles, suggesting that they can modulate FGF signaling among other cellular pathways. In contrast, compounds such as BGJ398 (Infigratinib) and LY2874455 present a more selective profile, predominantly targeting FGFRs. The diversity in these chemical structures and their corresponding selectivity profiles underscores the complexity of the FGF signaling pathway and the opportunities to modulate it at various levels..