Santa Cruz Biotechnology now offers a broad range of cGKI Substrates for use in various applications. cGKI, or cyclic GMP-dependent protein kinase I, is a critical enzyme that plays a significant role in a variety of cellular processes, including smooth muscle relaxation, platelet function, and neuronal signaling. cGKI Substrates are indispensable tools in scientific research, as they allow for the precise study of the phosphorylation events mediated by this kinase, which are essential for understanding how cyclic GMP signaling regulates cellular activities. Researchers utilize cGKI Substrates to investigate the specific targets of cGKI, exploring how phosphorylation by this kinase affects protein function, localization, and interactions within cells. These substrates are frequently employed in biochemical assays and cell-based studies to study the roles of cGKI in key physiological processes such as vascular tone regulation, synaptic plasticity, and cellular proliferation. By providing detailed insights into the mechanisms of cGKI action, these substrates have become essential for advancing our understanding of the complex signaling pathways that rely on cyclic GMP as a second messenger. The availability of cGKI Substrates has facilitated significant progress in research areas such as molecular biology, cardiovascular research, and neurobiology, where precise modulation and analysis of kinase activity are crucial. These substrates are particularly valuable in experiments designed to dissect the regulatory networks governing cellular responses to cyclic GMP, offering researchers the tools needed to explore the intricate balance of signaling pathways that maintain cellular homeostasis. View detailed information on our available cGKI Substrates by clicking on the product name.