CETP Inhibitors

CETP inhibitors belong to a specific class of chemical compounds that target and modulate the activity of Cholesteryl Ester Transfer Protein (CETP). This class of molecules is designed to interact with CETP, a protein involved in lipid metabolism and lipid transport within the body. CETP plays a crucial role in the transfer of cholesteryl esters and triglycerides between different lipoprotein particles, primarily high-density lipoproteins (HDL) and low-density lipoproteins (LDL). The primary function of CETP is to facilitate the exchange of lipids between these lipoprotein fractions, thereby influencing the overall distribution of cholesterol and other lipids in the bloodstream. CETP inhibitors, as the name suggests, work by inhibiting the activity of CETP, which can lead to alterations in the balance of various lipoprotein particles and their associated lipids. This class of compounds is of significant interest in research and development due to its implications for lipid metabolism regulation. The intricate role of CETP inhibitors in influencing lipid dynamics underscores their relevance in the broader context of lipid-related research.