Molecular structure of Chaetoviridin A
Chaetoviridin A (CAS 128252-98-2)
Alternate Names:
CCRIS 7226
Application:
Chaetoviridin A is Chaetoviridin A is an azaphilone antibiotic that inhibits MAO and CETP
CAS Number:
128252-98-2
Molecular Weight:
432.89
Molecular Formula:
C23H25ClO6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
Chaetoviridin A is a product isolated from the fungus Chaetomium virescens. It is a member of the chaetoviridin family of compounds, which has antifungal and antibacterial properties. Chaetoviridin A has a unique structure that includes a macrocyclic lactone ring and a tetramic acid moiety. Chaetoviridin A has antibacterial properties. Its mechanism of action involves disrupting key cellular processes in fungi and bacteria, making it valuable for studying the molecular basis of microbial pathogenesis. Chaetoviridin A represents a fascinating product with significant potential for further exploration in the field of biochemistry.
Chaetoviridin A (CAS 128252-98-2) References
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- Chaetoglobosins and azaphilones produced by Canadian strains of Chaetomium globosum isolated from the indoor environment. | McMullin, DR., et al. 2013. Mycotoxin Res. 29: 47-54. PMID: 23334724
- Expanding the structural diversity of polyketides by exploring the cofactor tolerance of an inline methyltransferase domain. | Winter, JM., et al. 2013. Org Lett. 15: 3774-7. PMID: 23837609
- Bioassays guided isolation of compounds from Chaetomium globosum. | Awad, NE., et al. 2014. J Mycol Med. 24: e35-42. PMID: 24361402
- Biochemical and Structural Basis for Controlling Chemical Modularity in Fungal Polyketide Biosynthesis. | Winter, JM., et al. 2015. J Am Chem Soc. 137: 9885-93. PMID: 26172141
- Potentially harmful secondary metabolites produced by indoor Chaetomium species on artificially and naturally contaminated building materials. | Došen, I., et al. 2017. Indoor Air. 27: 34-46. PMID: 26880675
- Fungal endophytes isolated from Protium heptaphyllum and Trattinnickia rhoifolia as antagonists of Fusarium oxysporum. | Fierro-Cruz, JE., et al. 2017. Rev Argent Microbiol. 49: 255-263. PMID: 28495036
- Chlorinated Azaphilone Pigments with Antimicrobial and Cytotoxic Activities Isolated from the Deep Sea Derived Fungus Chaetomium sp. NA-S01-R1. | Wang, W., et al. 2018. Mar Drugs. 16: PMID: 29438326
- The screening and identification of the biological control fungi Chaetomium spp. against wheat common root rot. | Yue, HM., et al. 2018. FEMS Microbiol Lett. 365: PMID: 30289449
- New Glutamine-Containing Azaphilone Alkaloids from Deep-Sea-Derived Fungus Chaetomium globosum HDN151398. | Sun, C., et al. 2019. Mar Drugs. 17: PMID: 31035362
- Cytotoxic Nitrogenated Azaphilones from the Deep-Sea-Derived Fungus Chaetomium globosum MP4-S01-7. | Wang, W., et al. 2020. J Nat Prod. 83: 1157-1166. PMID: 32193933
- Detection of Chaetomium globosum, Ch. cochliodes and Ch. rectangulare during the Diversity Tracking of Mycotoxin-Producing Chaetomium-Like Isolates Obtained in Buildings in Finland. | Salo, JM., et al. 2020. Toxins (Basel). 12: PMID: 32650391
- Antifungal Activity of Chaetoviridin A from Chaetomium globosum CEF-082 Metabolites Against Verticillium dahliae in Cotton. | Zhang, Y., et al. 2021. Mol Plant Microbe Interact. 34: 758-769. PMID: 33646818
- Azaphilones from the Endophyte Diaporthe sp. and Their Toxicity. | Huang, F., et al. 2022. Chem Biodivers. 19: e202200849. PMID: 36193753
- Azaphilones inhibit tumor promotion by 12-O-tetradecanoylphorbol-13-acetate in two-stage carcinogenesis in mice. | Yasukawa, K., et al. 1994. Oncology. 51: 108-12. PMID: 8265094
Inhibitor of:
CETP, and MAO.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Chaetoviridin A, 1 mg | sc-396533 | 1 mg | $154.00 | |||
Chaetoviridin A, 5 mg | sc-396533A | 5 mg | $560.00 |