CD92 inhibitors are a class of chemical compounds specifically designed to target and modulate the activity of the CD92 protein, also known as SLC44A1. CD92 is a member of the solute carrier family 44 (SLC44) and is involved in the transport of organic cations across cellular membranes. This protein plays a vital role in the regulation of cellular uptake and efflux of various molecules, including small organic cations and larger substrates. CD92 inhibitors are primarily utilized in molecular and cellular biology research to investigate the functional properties and regulatory mechanisms associated with this protein.
The development of CD92 inhibitors typically involves a combination of biochemical, biophysical, and structural approaches aimed at identifying or designing molecules that can selectively interact with CD92 and modulate its transport activity. By inhibiting CD92, these compounds can disrupt the transport of organic cations and other substrates mediated by this protein. Researchers use CD92 inhibitors to explore the intricate roles played by CD92 in cellular uptake and efflux processes, including its impact on cellular metabolism and homeostasis. Furthermore, these inhibitors serve as valuable tools for dissecting the broader network of cellular pathways involving organic cation transporters, contributing to our understanding of fundamental cell biology mechanisms and providing insights into avenues for further scientific inquiry.
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