Date published: 2025-11-1

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CCP6 Inhibitors

CCP6 inhibitors are a class of chemical compounds that play a crucial role in the field of molecular biology and biochemistry. These inhibitors are specifically designed to target and modulate the activity of CCP6, which stands for Clathrin-Coated Pit Protein 6. CCP6 is a protein involved in the process of endocytosis, a fundamental cellular mechanism responsible for the internalization of extracellular substances, such as nutrients and signaling molecules, into cells. By inhibiting CCP6, these compounds can exert a profound impact on the regulation of endocytosis, ultimately influencing various cellular processes and pathways.

The mechanism of action of CCP6 inhibitors typically involves binding to the CCP6 protein, thereby preventing it from fulfilling its normal cellular functions. This interference can disrupt the formation and stability of clathrin-coated pits, specialized structures on the cell membrane responsible for cargo uptake during endocytosis. As a result, the internalization of specific molecules or receptors may be impaired, leading to downstream effects on cellular signaling, membrane trafficking, and overall cell physiology. Researchers have been keenly interested in the development and study of CCP6 inhibitors due to their potential implications in understanding fundamental cellular processes and their involvement in various diseases.

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

TC-E 5003

17328-16-4sc-397056
50 mg
$148.00
3
(0)

Binds to the active site of CCP6, preventing deubiquitination.

WP1130

856243-80-6sc-364650
sc-364650A
10 mg
50 mg
$480.00
$1455.00
1
(0)

Promotes degradation of CCP6 by inhibiting deubiquitinase activity.

IU1

314245-33-5sc-361215
sc-361215A
sc-361215B
10 mg
50 mg
100 mg
$138.00
$607.00
$866.00
2
(0)

Allosteric inhibitor that modulates CCP6 activity.

PR 619

2645-32-1sc-476324
sc-476324A
sc-476324B
1 mg
5 mg
25 mg
$75.00
$184.00
$423.00
1
(0)

Broad-spectrum deubiquitinase inhibitor, including CCP6.

UCH-L1 Inhibitor Inhibitor

668467-91-2sc-356182
10 mg
$200.00
1
(1)

Interferes with CCP6's catalytic activity, preventing ubiquitin removal.

NSC 632839 hydrochloride

157654-67-6sc-204138
sc-204138A
10 mg
50 mg
$119.00
$465.00
(0)

Interferes with CCP6's catalytic activity, inhibiting ubiquitin removal.