Coiled-Coil Domain Containing Protein Inhibitors refer to a class of chemicals that indirectly affect proteins with coiled-coil domains, such as CCDC87, by targeting pathways or cellular processes related to these proteins. These inhibitors work by modulating the activity of proteins or signaling cascades that interact with or regulate coiled-coil domain-containing proteins.The coiled-coil domain is a structural motif involved in the formation of alpha-helical coiled-coil assemblies, which are crucial in various cellular processes, including vesicular trafficking, cytoskeletal dynamics, and cell signaling. Inhibitors targeting these processes can indirectly influence proteins like CCDC87 by altering the cellular environment in which they operate. For example, inhibitors that affect microtubule dynamics might impact proteins involved in vesicular transport, potentially modulating the function or localization of CCDC87.
Moreover, the signaling pathways associated with coiled-coil proteins often involve key regulatory proteins like kinases or phosphatases. By using inhibitors that target these regulatory proteins, one can indirectly affect the signaling pathways in which coiled-coil domain-containing proteins participate. This strategy can lead to changes in the activation state, expression levels, or interaction networks of these proteins, thereby influencing their overall function in the cell.In summary, while direct inhibitors of CCDC87 are not available, exploring the broader context of coiled-coil domain protein functions and interactions allows for the identification of potential indirect inhibitors. These inhibitors offer a means to study and modulate the biological roles of CCDC87 and similar proteins, contributing to our understanding of their functions in cellular processes.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Colchicine | 64-86-8 | sc-203005 sc-203005A sc-203005B sc-203005C sc-203005D sc-203005E | 1 g 5 g 50 g 100 g 500 g 1 kg | $98.00 $315.00 $2244.00 $4396.00 $17850.00 $34068.00 | 3 | |
Colchicine binds to tubulin, disrupting microtubule polymerization, which can affect proteins involved in vesicular transport and cytoskeletal organization, potentially impacting CCDC87-associated processes. | ||||||
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $40.00 $73.00 $217.00 $242.00 $724.00 $1196.00 | 39 | |
Paclitaxel stabilizes microtubules, inhibiting their disassembly. This can influence the dynamics of proteins associated with microtubule-dependent processes, possibly affecting CCDC87. | ||||||
Vinblastine | 865-21-4 | sc-491749 sc-491749A sc-491749B sc-491749C sc-491749D | 10 mg 50 mg 100 mg 500 mg 1 g | $100.00 $230.00 $450.00 $1715.00 $2900.00 | 4 | |
Vinblastine inhibits microtubule assembly. By altering microtubule dynamics, it can indirectly affect coiled-coil domain-containing proteins involved in cell structure and transport. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $58.00 $83.00 $140.00 $242.00 | 38 | |
Nocodazole disrupts microtubule polymerization. Its effects on the microtubule network can indirectly influence proteins like CCDC87 that may be involved in cellular transport and signaling. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $182.00 $693.00 | 88 | |
Y-27632 is a ROCK inhibitor, affecting actin cytoskeleton dynamics. This can indirectly influence coiled-coil domain proteins involved in cellular structure and motility. | ||||||
(S)-(−)-Blebbistatin | 856925-71-8 | sc-204253 sc-204253A sc-204253B sc-204253C | 1 mg 5 mg 10 mg 25 mg | $71.00 $260.00 $485.00 $949.00 | ||
Blebbistatin inhibits myosin II, impacting cellular contractility and motility. It may affect the function or localization of coiled-coil domain proteins like CCDC87. | ||||||
ML-7 hydrochloride | 110448-33-4 | sc-200557 sc-200557A | 10 mg 50 mg | $89.00 $262.00 | 13 | |
ML-7 is an inhibitor of myosin light chain kinase (MLCK), which can alter actin dynamics, potentially affecting proteins with coiled-coil domains involved in cellular architecture. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
PD 98059 is a MEK inhibitor, affecting MAPK/ERK signaling pathways. This can indirectly influence coiled-coil domain proteins involved in signal transduction processes. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002 is a PI3K inhibitor, affecting various signaling pathways, including those that might intersect with coiled-coil domain protein functions. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Rapamycin inhibits mTOR, affecting cell growth and proliferation pathways. This can indirectly influence coiled-coil domain proteins involved in these processes. | ||||||