CCDC45 Inhibitors
Kinase inhibitors such as staurosporine, Wortmannin, LY294002, and Roscovitine can attenuate signaling pathways that may govern the activity or expression of CCDC45. Similarly, compounds that affect cellular growth and metabolism, such as rapamycin, can modulate protein synthesis and potentially influence the function or levels of CCDC45. Cycloheximide and MG132 might affect CCDC45 by altering the synthesis and degradation balance of the protein, respectively.
Compounds that interfere with genetic material processing, like Mitomycin C and 5-Azacytidine, may affect the transcriptional regulation of the CCDC45 gene, while Brefeldin A's impact on protein trafficking could influence the localization and, consequently, the function of CCDC45 within the cell. Taxol, by affecting microtubule dynamics, could influence cell cycle-related proteins, potentially including CCDC45 if it is associated with cell division. U0126's inhibition of the MEK pathway could affect various proteins in the MAPK/ERK pathway, possibly including CCDC45 if it plays a role in this signaling cascade.
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Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
A potent kinase inhibitor that can inhibit many kinases within signaling pathways, potentially affecting CCDC45 function. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
A PI3K inhibitor that can alter downstream signaling, thereby possibly influencing CCDC45-related pathways. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
Another PI3K inhibitor that can disrupt PI3K-Akt signaling, potentially affecting CCDC45 activity. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
An mTOR inhibitor that can modulate cell growth and protein synthesis pathways, potentially altering CCDC45 function. | ||||||
Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $40.00 $82.00 $256.00 | 127 | |
Inhibits protein synthesis by interfering with the translocation step in protein synthesis, which could affect CCDC45 levels. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $56.00 $260.00 $980.00 | 163 | |
A proteasome inhibitor that can increase protein levels by preventing degradation, potentially affecting CCDC45 turnover. | ||||||
Mitomycin C | 50-07-7 | sc-3514A sc-3514 sc-3514B | 2 mg 5 mg 10 mg | $65.00 $99.00 $140.00 | 85 | |
Crosslinks DNA, potentially affecting the transcription of genes including those related to CCDC45 expression. | ||||||
Brefeldin A | 20350-15-6 | sc-200861C sc-200861 sc-200861A sc-200861B | 1 mg 5 mg 25 mg 100 mg | $30.00 $52.00 $122.00 $367.00 | 25 | |
Disrupts protein trafficking by inhibiting protein transport from the ER to the Golgi apparatus, which may influence CCDC45 localization or function. | ||||||
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $40.00 $73.00 $217.00 $242.00 $724.00 $1196.00 | 39 | |
Stabilizes microtubules and can disrupt cell division, potentially affecting CCDC45 if it's involved in cell cycle regulation. | ||||||
Roscovitine | 186692-46-6 | sc-24002 sc-24002A | 1 mg 5 mg | $92.00 $260.00 | 42 | |
A cyclin-dependent kinase inhibitor that can interfere with cell cycle progression and potentially CCDC45 function. | ||||||