CCDC159 Activators
CCDC159 Activators encompass a range of chemical compounds that indirectly enhance the functional activity of CCDC159 through various cellular mechanisms. Forskolin and IBMX both work by increasing intracellular cAMP levels, which could enhance CCDC159's function if it is involved in cAMP-dependent processes. Ionomycin and A23187, as calcium ionophores, would elevate intracellular calcium levels, potentially influencing CCDC159 if it has a role in calcium-dependent pathways. PMA, through the activation of protein kinase C, could modify CCDC159 activity within PKC-dependent signaling routes. Okadaic Acid, by inhibiting protein phosphatases, may lead to a state of increased phosphorylation which could affect CCDC159 activity if it is regulated by phosphorylation status.
Further influencing the activity of CCDC159 are compounds like LY294002 and PD98059, which target the PI3K/AKT and MAPK/ERK pathways, respectively. If CCDC159 is part of these pathways, its activity could be increased through these inhibitors' actions. Thapsigargin, by disrupting calcium homeostasis, could also impact CCDC159's function if CCDC159 is involved incalcium signaling. Genistein, by inhibiting tyrosine kinases, and Epigallocatechin Gallate, by affecting multiple signaling pathways, could each provide an environment where CCDC159's activity is upregulated if it is part of tyrosine kinase-dependent pathways. Lastly, the lipid signaling molecule Sphingosine-1-phosphate may enhance CCDC159 function by modulating sphingolipid signaling pathways. Collectively, these compounds represent a diversified approach to potentially augmenting the activity of CCDC159 by targeting different, yet specific, cellular mechanisms and pathways that could logically intersect with the functional role of CCDC159.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin activates adenylyl cyclase, which increases intracellular cAMP levels, leading to the activation of PKA. PKA can then phosphorylate various proteins, potentially including CCDC159 or proteins interacting with CCDC159, to enhance its functional activity. | ||||||
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $159.00 $315.00 $598.00 | 34 | |
IBMX is a non-selective inhibitor of phosphodiesterases, which prevents the breakdown of cAMP and cGMP, leading to their accumulation. The increased levels of cAMP can then activate PKA, which may indirectly enhance the activity of CCDC159. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
PMA is an activator of protein kinase C (PKC), which is involved in various signaling pathways. PKC activation can lead to downstream effects that could enhance the functional activity of CCDC159 by modulating proteins that interact with or regulate CCDC159. | ||||||
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $76.00 $265.00 | 80 | |
Ionomycin is a calcium ionophore that increases intracellular calcium levels, potentially affecting calcium-dependent protein kinases and phosphatases that could modulate the activity of CCDC159. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
EGCG is known to inhibit several protein kinases, potentially altering signaling pathways that might intersect with those regulated by CCDC159, thus indirectly enhancing its activity. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002 is an inhibitor of PI3K, which could lead to alterations in the downstream AKT signaling pathway, potentially affecting the functional activity of CCDC159. | ||||||
D-erythro-Sphingosine-1-phosphate | 26993-30-6 | sc-201383 sc-201383D sc-201383A sc-201383B sc-201383C | 1 mg 2 mg 5 mg 10 mg 25 mg | $162.00 $316.00 $559.00 $889.00 $1693.00 | 7 | |
Sphingosine-1-phosphate is involved in the sphingolipid signaling pathway, which can influence a variety of cellular processes, potentially including those regulated by CCDC159, thus indirectly enhancing its activity. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $94.00 $349.00 | 114 | |
Thapsigargin is a SERCA pump inhibitor, leading to increased cytosolic calcium levels, which could activate calcium-dependent signaling pathways and potentially enhance the activity of CCDC159. | ||||||
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
Staurosporine is a broad-spectrum protein kinase inhibitor, which could lead to selective activation of signaling pathways involving CCDC159 by inhibiting kinases that negatively regulate CCDC159 or its associated pathways. | ||||||
Dibutyryl-cAMP | 16980-89-5 | sc-201567 sc-201567A sc-201567B sc-201567C | 20 mg 100 mg 500 mg 10 g | $45.00 $130.00 $480.00 $4450.00 | 74 | |
Dibutyryl-cAMP is a cell-permeable cAMP analog that activates PKA and could thus indirectly enhance the activity of CCDC159 by modulating the phosphorylation state of CCDC159 or its interacting proteins. | ||||||