Cbl Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
CASIN | 425399-05-9 | sc-397016 | 10 mg | $460.00 | 1 | |
CASIN is a small molecule inhibitor that specifically targets the Crk-associated substrate (CAS) family proteins, including Cbl. It disrupts the interaction between CAS and Cbl, inhibiting Cbl-mediated ubiquitination and downregulating signaling pathways dependent on Cbl activity. | ||||||
WP1130 | 856243-80-6 | sc-364650 sc-364650A | 10 mg 50 mg | $490.00 $1484.00 | 1 | |
WP1130 is a small molecule inhibitor that targets deubiquitinases (DUBs), including Cbl-b. By inhibiting DUB activity, it increases the ubiquitination and degradation of Cbl-b, resulting in altered downstream signaling pathways regulated by Cbl-b. | ||||||
Nilotinib | 641571-10-0 | sc-202245 sc-202245A | 10 mg 25 mg | $209.00 $413.00 | 9 | |
Nilotinib is a tyrosine kinase inhibitor that can indirectly affect Cbl function. By inhibiting specific tyrosine kinases, it may modulate upstream signaling events that lead to Cbl activation or Cbl-dependent signaling pathways. | ||||||
1-Naphthyl PP1 | 221243-82-9 | sc-203765 sc-203765A | 10 mg 50 mg | $235.00 $983.00 | 3 | |
1-Naphthyl PP1 is a synthetic compound that has been suggested to inhibit Cbl activity. Its specific mechanism of action on Cbl is not well-characterized. | ||||||
Dansylcadaverine | 10121-91-2 | sc-214851 sc-214851A sc-214851B | 100 mg 250 mg 1 g | $52.00 $89.00 $240.00 | 4 | |
Dansylcadaverine is a small molecule that can inhibit Cbl activity by interfering with the ubiquitination process. It competes with ubiquitin for binding to E2 enzymes, preventing Cbl from transferring ubiquitin to its target substrates, leading to reduced Cbl-dependent ubiquitination and signaling. | ||||||
Imatinib | 152459-95-5 | sc-267106 sc-267106A sc-267106B | 10 mg 100 mg 1 g | $26.00 $119.00 $213.00 | 27 | |
Imatinib is a tyrosine kinase inhibitor that indirectly affects Cbl function. By inhibiting specific tyrosine kinases, it may modulate upstream signaling events that lead to Cbl activation or Cbl-dependent signaling pathways. | ||||||
Acacetin | 480-44-4 | sc-239178 | 25 mg | $260.00 | 2 | |
Acacetin is a natural compound that may modulate Cbl activity. Its specific mechanism of action on Cbl is not well-established. | ||||||
F16 | 36098-33-6 | sc-202604 | 25 mg | $195.00 | ||
F16 is a small molecule inhibitor that has been suggested to inhibit Cbl activity. Its specific mechanism of action on Cbl is not well-characterized. | ||||||