Molecular structure of F16, CAS Number: 36098-33-6
F16 (CAS 36098-33-6)
Alternate Names:
4-[(E)-2-(Indol-3-yl)ethenyl]-N-methylpyridinium iodide
Application:
F16 is a cell-permeable mitochondrial toxin with apoptotic and necrotic action in tumor cell lines
CAS Number:
36098-33-6
Molecular Weight:
362.2
Molecular Formula:
C16H15IN2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
F16 is a cell-permeable, fluorogenic, delocalized lipophilic cationic compound that acts as a mitochondrial toxin and possesses the dual ability to induce apoptosis as well as necrosis in tumor cells. F16 preferentially accumulates in mitochondria, inhibits oxidative phosphorylation and causes mitochondrial transmembrane depolarization. The incorporation and localization of F16 can be easily monitored by its fluorescence property.
F16 (CAS 36098-33-6) References
Fantin, V.R., and Leder, P. 2004. Cancer Res. 64, 329. Fantin, V.R., et al. 2002. Cancer Cell 2, 29.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
F16, 25 mg | sc-202604 | 25 mg | $195.00 |