CB2 Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
AM-630 | 164178-33-0 | sc-200365B sc-200365 sc-200365A sc-200365C | 5 mg 10 mg 50 mg 100 mg | $76.00 $163.00 $622.00 $852.00 | 8 | |
AM-630 is characterized by its unique ability to selectively antagonize the CB2 receptor, primarily through hydrophobic interactions and specific hydrogen bonding with key amino acid residues. Its structural conformation allows for effective steric hindrance, preventing receptor activation. The compound's moderate lipophilicity enhances its affinity for lipid membranes, influencing its distribution and interaction with cellular signaling pathways, ultimately modulating receptor activity and downstream effects. | ||||||
SR 144528 | 192703-06-3 | sc-224292 sc-224292A | 5 mg 10 mg | $282.00 $539.00 | 6 | |
This compound functions as a selective CB2 receptor antagonist, blocking CB2 receptor activation and often used for research purposes. | ||||||
JTE 907 | 282089-49-0 | sc-203616 sc-203616A | 10 mg 50 mg | $283.00 $1100.00 | ||
JTE 907 exhibits a distinctive profile as a selective CB2 receptor modulator, engaging in intricate molecular interactions that include π-π stacking and van der Waals forces with receptor binding sites. Its unique spatial arrangement facilitates a conformational fit that alters receptor dynamics, influencing downstream signaling cascades. The compound's high lipophilicity promotes membrane penetration, enhancing its bioavailability and interaction with lipid-rich environments, thereby affecting cellular responses. | ||||||
AM 404 | 183718-77-6 | sc-207275 | 10 mg | $118.00 | ||
AM 404 is characterized by its selective affinity for the CB2 receptor, where it engages in specific hydrogen bonding and hydrophobic interactions that stabilize its binding. This compound's unique structural features allow it to induce conformational changes in the receptor, modulating its activity and influencing intracellular signaling pathways. Additionally, AM 404's solubility properties enhance its distribution within lipid membranes, impacting its interaction with cellular components and overall biological behavior. | ||||||
(S)-SLV 319 | 464213-10-3 | sc-222285 sc-222285A | 1 mg 5 mg | $92.00 $311.00 | ||
(S)-SLV 319 exhibits a high degree of selectivity for the CB2 receptor, facilitated by its unique stereochemistry that promotes optimal spatial orientation for binding. This compound engages in intricate van der Waals interactions and electrostatic forces, enhancing its affinity. Its dynamic molecular conformation allows for rapid receptor activation, influencing downstream signaling cascades. Furthermore, (S)-SLV 319's lipophilicity aids in membrane penetration, affecting its bioavailability and interaction with lipid-rich environments. | ||||||
URB447 | 1132922-57-6 | sc-224347 sc-224347A | 5 mg 10 mg | $132.00 $250.00 | ||
URB447 is characterized by its selective affinity for the CB2 receptor, driven by its unique structural features that enable precise molecular docking. The compound's ability to form hydrogen bonds and engage in hydrophobic interactions enhances its binding stability. Additionally, URB447's conformational flexibility allows for efficient receptor engagement, facilitating swift activation of intracellular signaling pathways. Its moderate lipophilicity also influences its distribution within lipid membranes, impacting its overall behavior in biological systems. | ||||||
O-1821 | 35482-50-9 | sc-205417 sc-205417A | 1 mg 5 mg | $31.00 $121.00 | ||
O-1821 exhibits a remarkable selectivity for the CB2 receptor, attributed to its distinctive steric configuration that promotes effective molecular recognition. The compound's reactivity as an acid halide facilitates nucleophilic attack, leading to rapid formation of covalent bonds with target biomolecules. Its unique electronic properties enhance electrophilicity, allowing for specific interactions that modulate downstream signaling pathways. Furthermore, O-1821's solubility characteristics influence its diffusion across cellular membranes, affecting its bioavailability and interaction dynamics. | ||||||
BML-190 | 2854-32-2 | sc-203533 sc-203533A | 10 mg 50 mg | $78.00 $326.00 | ||
BML-190 is characterized by its high affinity for the CB2 receptor, driven by its unique spatial arrangement that optimizes binding interactions. As an acid halide, it undergoes swift nucleophilic reactions, enabling the formation of stable adducts with various biological targets. Its distinctive electronic structure enhances its reactivity, promoting selective interactions that can influence cellular signaling cascades. Additionally, BML-190's solubility profile plays a crucial role in its distribution and interaction within biological systems. | ||||||
CB-52 | sc-221404 sc-221404A | 1 mg 5 mg | $39.00 $173.00 | |||
CB-52 exhibits a remarkable selectivity for the CB2 receptor, attributed to its unique steric configuration that facilitates precise molecular docking. As an acid halide, it engages in rapid acylation reactions, allowing for the efficient formation of covalent bonds with nucleophiles. Its electronic characteristics contribute to a heightened reactivity, enabling targeted modulation of signaling pathways. Furthermore, CB-52's solubility characteristics enhance its bioavailability and interaction dynamics within complex biological environments. | ||||||
QNZ | 545380-34-5 | sc-200675 | 1 mg | $115.00 | 12 | |
Research suggests that CAY10470, a CB2 receptor agonist, may reduce inflammation and oxidative stress. | ||||||