caspase-11 Inhibitors
Items 1 to 10 of 11 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Wedelolactone | 524-12-9 | sc-200648 sc-200648A | 1 mg 5 mg | $108.00 $330.00 | 8 | |
Wedelolactone is a naturally occurring compound that exhibits unique interactions with caspase-11, influencing inflammatory pathways. It selectively binds to the enzyme, modulating its activity and altering downstream signaling cascades. The compound's structural features promote specific molecular recognition, enhancing its efficacy in regulating caspase-11-mediated processes. This interaction can lead to distinct reaction kinetics, providing insights into cellular responses to stress and inflammation. | ||||||
VX-765 | 273404-37-8 | sc-475845 sc-475845A sc-475845B | 5 mg 10 mg 50 mg | $224.00 $296.00 $949.00 | 1 | |
A caspase-1 inhibitor that may indirectly influence caspase-11 activity due to the close interplay between caspase-1 and caspase-11 in inflammasome signaling. | ||||||
Z-VAD-FMK | 187389-52-2 | sc-3067 | 500 µg | $74.00 | 256 | |
A pan-caspase inhibitor that, while broadly targeting caspases, could potentially inhibit caspase-11, affecting its role in pyroptosis and inflammation. | ||||||
Caspase-1 Inhibitor II | 178603-78-6 | sc-300323 sc-300323A | 5 mg 25 mg | $255.00 $1224.00 | 7 | |
This compound might indirectly affect caspase-11 by modulating inflammasome activity and the subsequent activation of inflammatory cascades. | ||||||
Parthenolide | 20554-84-1 | sc-3523 sc-3523A | 50 mg 250 mg | $79.00 $300.00 | 32 | |
Targets NF-κB signaling, which is involved in the regulation of inflammatory responses. By inhibiting NF-κB, parthenolide may indirectly reduce caspase-11 activation. | ||||||
Resatorvid | 243984-11-4 | sc-476758 | 5 mg | $360.00 | ||
A selective inhibitor of Toll-like receptor 4 (TLR4). Since TLR4 signaling can induce caspase-11 activation, inhibiting TLR4 could indirectly reduce caspase-11 activity. | ||||||
Pyrrolidinedithiocarbamic acid ammonium salt | 5108-96-3 | sc-203224 sc-203224A | 5 g 25 g | $32.00 $63.00 | 11 | |
Pyrrolidinedithiocarbamic acid ammonium salt can modulate the inflammatory response. By inhibiting NF-κB, PDTC might indirectly reduce the activation of caspase-11. | ||||||
Anakinra | 143090-92-0 | sc-507486 | 10 mg | $795.00 | ||
An IL-1 receptor antagonist. While it does not directly inhibit caspase-11, by blocking IL-1 signaling, anakinra can indirectly modulate the inflammasome pathway in which caspase-11 is involved. | ||||||
BAY 11-7085 | 196309-76-9 | sc-202490 sc-202490A | 10 mg 50 mg | $122.00 $516.00 | 55 | |
Inhibits IκBα phosphorylation, thus modulating NF-κB signaling. This may indirectly affect caspase-11 activity through the regulation of inflammatory pathways. | ||||||
Glyburide (Glibenclamide) | 10238-21-8 | sc-200982 sc-200982A sc-200982D sc-200982B sc-200982C | 1 g 5 g 25 g 100 g 500 g | $45.00 $60.00 $115.00 $170.00 $520.00 | 36 | |
Known to inhibit the NLRP3 inflammasome. This inhibition can indirectly reduce caspase-11 activity linked to NLRP3-mediated signaling pathways. | ||||||