CASD1 Inhibitors
CASD1 inhibitors are a specialized class of chemical compounds designed to specifically target and inhibit the function of CASD1, a protein encoded by the CASD1 gene. This protein is implicated in various cellular processes, including signal transduction pathways and cellular homeostasis. The inhibitors work by binding to the CASD1 protein or interfering with its signaling pathways, leading to a reduction in its activity. The precise mechanism of action for each CASD1 inhibitor can vary depending on the structure and target site of the compound. Some inhibitors may bind directly to the active site of the protein, effectively blocking its ability to interact with other molecules or substrates. Others might interfere with the upstream signaling elements that regulate CASD1 activity or its post-translational modifications, which are critical for its proper functioning. The chemical structure of these inhibitors is crucial as it determines the specificity and affinity for CASD1, as well as their ability to cross cellular membranes to reach their target.
The development of CASD1 inhibitors involves rigorous analysis of the protein's structure and the signaling pathways it participates in. Researchers aim to create compounds with high binding affinity and specificity to ensure that the inhibition of CASD1 is efficient and selective, minimizing off-target effects. Typically, these inhibitors are small molecules that can easily diffuse through the cell membrane to reach intracellular targets. Upon reaching the CASD1 protein, the inhibitors induce a conformational change or occupy its active site, preventing the normal action of the protein. The inhibition of CASD1 can lead to a cascade of effects downstream in the signaling pathway, culminating in the alteration of specific cellular functions that the protein regulates. By understanding the intricate details of the protein's role in the cell, scientists can predict the consequences of its inhibition and design inhibitors that can precisely modulate its activity for desired cellular outcomes.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
GW 5074 | 220904-83-6 | sc-200639 sc-200639A | 5 mg 25 mg | $106.00 $417.00 | 10 | |
GW5074 is a Raf kinase inhibitor which hinders the Raf/MEK/ERK pathway. CASD1, being a part of cellular signaling processes, would exhibit decreased functional activity due to the downregulation of the ERK pathway, which is crucial for various cellular functions including growth and differentiation. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002 is a PI3K inhibitor that blocks the PI3K/AKT pathway. CASD1, if reliant on the AKT pathway for any aspect of its function, would be indirectly inhibited as the AKT pathway influences numerous cellular processes including metabolism, proliferation, cell survival, growth, and angiogenesis. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
PD98059 is a MEK inhibitor, which specifically blocks the activation of MAPK/ERK kinase, leading to the inhibition of the MAPK/ERK pathway. This pathway is involved in the regulation of gene expression and cellular proliferation, which could impact the function of CASD1 if it is linked to these cellular processes. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Rapamycin is an mTOR inhibitor which disrupts the mTORC1 pathway, potentially leading to reduced protein synthesis and cell growth. If CASD1 function is associated with the mTOR signaling pathway, its activity would be indirectly diminished by rapamycin. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125 is a JNK inhibitor that impedes the JNK signaling which is involved in the control of gene expression and cellular apoptosis. The inhibition of this pathway can indirectly affect CASD1 if its function is tied to these cellular outcomes. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
SB203580 is a p38 MAPK inhibitor that blocks p38-mediated signaling pathways critical for inflammatory responses and differentiation. If CASD1 plays a role in these pathways, its activity would be indirectly affected by this inhibitor. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $63.00 $241.00 | 136 | |
U0126 is another MEK inhibitor that blocks MEK1/2, which are upstream regulators of ERK. Inhibition of this pathway would affect CASD1 if it is involved in the cellular processes that are regulated by the ERK pathway. | ||||||
WZ 4002 | 1213269-23-8 | sc-364655 sc-364655A | 10 mg 50 mg | $180.00 $744.00 | 1 | |
WZ4002 is an EGFR inhibitor that could potentially indirectly influence CASD1 if it is involved in signaling pathways downstream of EGFR, which is important for cell proliferation and survival. | ||||||
Leflunomide | 75706-12-6 | sc-202209 sc-202209A | 10 mg 50 mg | $20.00 $81.00 | 5 | |
Leflunomide is a pyrimidine synthesis inhibitor that hampers the production of RNA and DNA. If CASD1's function is related to nucleotide synthesis or utilization, this inhibition would impact its activity. | ||||||
Imatinib | 152459-95-5 | sc-267106 sc-267106A sc-267106B | 10 mg 100 mg 1 g | $25.00 $117.00 $209.00 | 27 | |
Imatinib is a tyrosine kinase inhibitor that can affect CASD1 if it is involved in signaling pathways or cellular processes regulated by BCR-ABL, c-KIT, and PDGFR tyrosine kinases. | ||||||