Calcium Channel Modulators
Items 151 to 160 of 167 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
N-Desmethyl Diltiazem Hydrochloride | 130606-60-9 | sc-219119 sc-219119A sc-219119B sc-219119C | 10 mg 25 mg 50 mg 100 mg | $418.00 $908.00 $1533.00 $2448.00 | ||
N-Desmethyl Diltiazem Hydrochloride functions as a calcium channel modulator by engaging with voltage-gated calcium channels, leading to a conformational change that affects ion permeability. Its unique structure allows for specific hydrogen bonding interactions with channel residues, enhancing its binding affinity. This compound also exhibits distinct kinetic properties, with a notable impact on calcium influx regulation, influencing cellular excitability and signaling pathways. | ||||||
(-)-Nitrendipine | 80873-62-7 | sc-478337 | 5 mg | $380.00 | ||
(-)-Nitrendipine acts as a calcium channel modulator by selectively binding to L-type calcium channels, inducing a unique allosteric effect that alters channel dynamics. Its stereochemical configuration facilitates a slower dissociation rate, enhancing its modulatory effects. Additionally, this compound interacts with membrane microdomains, potentially altering lipid composition and fluidity, which can further influence channel behavior and calcium homeostasis within cellular environments. | ||||||
ent-Calindol Hydrochloride | 728930-30-1 | sc-211409 | 10 mg | $360.00 | ||
ent-Calindol Hydrochloride acts as a calcium channel modulator by selectively interacting with L-type calcium channels, promoting alterations in channel gating dynamics. Its unique stereochemistry facilitates specific electrostatic interactions with channel domains, enhancing its modulatory effects. The compound demonstrates distinctive reaction kinetics, characterized by a rapid onset of action and prolonged modulation, which can significantly influence calcium homeostasis and cellular signaling cascades. | ||||||
Gliquidone | 33342-05-1 | sc-295010 sc-295010A | 1 g 5 g | $116.00 $240.00 | ||
Gliquidone functions as a calcium channel modulator by engaging with voltage-gated calcium channels, particularly influencing their conformational states. Its unique structural features allow for specific binding interactions that stabilize the inactivated state of the channels, thereby altering calcium influx. This modulation is characterized by a distinct time-dependent response, leading to nuanced changes in intracellular calcium levels and subsequent signaling pathways, showcasing its intricate role in cellular physiology. | ||||||
D-Glucose 6-phosphate solution | 56-73-5 | sc-485583 sc-485583A | 500 mg 1 g | $114.00 $198.00 | ||
D-Glucose 6-phosphate solution acts as a calcium channel modulator by influencing the phosphorylation state of proteins involved in calcium signaling. Its unique ability to interact with key regulatory enzymes alters the dynamics of calcium release from intracellular stores. This modulation is characterized by a rapid onset of action, affecting the kinetics of calcium-dependent processes and enhancing the sensitivity of cellular responses to calcium fluctuations, thereby playing a critical role in metabolic regulation. | ||||||
rac Felodipine-d3 | 1189970-31-7 | sc-219831 | 1 mg | $330.00 | ||
Rac Felodipine-d3 functions as a calcium channel modulator by selectively binding to L-type calcium channels, altering their conformation and gating properties. This interaction leads to a nuanced modulation of calcium influx, influencing downstream signaling pathways. Its isotopic labeling allows for precise tracking in biochemical assays, providing insights into reaction kinetics and channel dynamics. The compound's unique structure enhances its specificity, making it a valuable tool for studying calcium-mediated cellular processes. | ||||||
(R)-(+)-Felodipine-d5 | sc-219730 | 1 mg | $490.00 | |||
(R)-(+)-Felodipine-d5 acts as a calcium channel modulator by engaging with L-type calcium channels, inducing specific conformational changes that affect ion permeability. The deuterated form offers enhanced stability and distinct isotopic signatures, facilitating advanced spectroscopic studies. Its unique stereochemistry contributes to selective interactions, allowing for detailed exploration of calcium-dependent signaling mechanisms and the kinetics of channel activation and inactivation. | ||||||
Diltiazem-d3 Hydrochloride | 1217623-80-7 | sc-218225 sc-218225B sc-218225A | 1 mg 5 mg 10 mg | $290.00 $330.00 $660.00 | 1 | |
Diltiazem-d3 Hydrochloride functions as a calcium channel modulator by selectively binding to L-type calcium channels, leading to alterations in their gating dynamics. The incorporation of deuterium enhances its isotopic labeling, providing insights into molecular interactions through advanced NMR techniques. Its unique structural features promote specific binding affinities, enabling the investigation of calcium influx regulation and the modulation of cellular excitability in various experimental contexts. | ||||||
Pinaverium-d4 Bromide | sc-219623 | 1 mg | $380.00 | |||
Pinaverium-d4 Bromide acts as a calcium channel modulator by interacting with voltage-gated calcium channels, influencing their conformational states. The presence of deuterium isotopes allows for enhanced tracking of molecular dynamics in kinetic studies. Its distinct stereochemistry facilitates selective interactions with specific channel subtypes, providing a unique platform for exploring calcium signaling pathways and their regulatory mechanisms in cellular environments. | ||||||
Naspm trihydrochloride | 1049731-36-3 | sc-361272 sc-361272A | 25 mg 250 mg | $312.00 $1977.00 | 2 | |
Naspm trihydrochloride functions as a calcium channel modulator by selectively binding to and stabilizing the inactivated state of calcium channels. This unique interaction alters the channel's gating kinetics, leading to a distinct modulation of calcium influx. Its trihydrochloride form enhances solubility and bioavailability, allowing for more effective exploration of calcium-dependent processes. The compound's specific binding affinity contributes to its role in dissecting calcium signaling intricacies. | ||||||