cadherin-20 Activators
Cadherin-20 activators are compounds that, while not directly interacting with cadherin-20, create conditions that can promote the functional activity of this protein. These chemicals exert their effects through a variety of mechanisms, such as modifying the intracellular calcium concentration, influencing the phosphorylation status of proteins involved in cadherin function, or altering the cytoskeletal architecture to facilitate cadherin-mediated cell adhesion. The interaction between these chemicals and cellular pathways underscores the complex regulation of cadherin-20, wherein changes in the cellular environment can result in modulated cadherin activity.
These compounds are integral to cellular processes that establish and maintain the proper function of cadherin-20. For instance, by adjusting the calcium milieu through either direct supplementation or chelation, cells may alter the adhesive properties that cadherins mediate. Similarly, modulating the actin cytoskeleton with compounds that affect actin polymerization or stabilization can indirectly impact cadherin-based adhesion.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Calcium chloride anhydrous | 10043-52-4 | sc-207392 sc-207392A | 100 g 500 g | $65.00 $262.00 | 1 | |
Enhances calcium concentration, which is fundamental for cadherin-mediated cell adhesion, potentially supporting cadherin-20 function. | ||||||
Magnesium chloride | 7786-30-3 | sc-255260C sc-255260B sc-255260 sc-255260A | 10 g 25 g 100 g 500 g | $27.00 $34.00 $47.00 $123.00 | 2 | |
Magnesium can modulate the cellular use of calcium, indirectly influencing cadherin-mediated adhesion processes. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Glycogen synthase kinase 3 (GSK-3) inhibitor, can modulate signaling pathways that affect cell adhesion dynamics. | ||||||
Manganese(II) chloride beads | 7773-01-5 | sc-252989 sc-252989A | 100 g 500 g | $19.00 $30.00 | ||
Manganese is required for the activation of certain kinases and phosphatases that could affect cadherin function. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
An activator of protein kinase C (PKC) which can influence pathways involved in cell adhesion and cadherin function. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $58.00 $83.00 $140.00 $242.00 | 38 | |
Disrupts microtubule networks, which can impact cell shape and adhesion properties, indirectly affecting cadherin signaling. | ||||||
Jasplakinolide | 102396-24-7 | sc-202191 sc-202191A | 50 µg 100 µg | $180.00 $299.00 | 59 | |
Stabilizes actin filaments, potentially affecting cadherin function through changes in the cytoskeleton. | ||||||
W-7 | 61714-27-0 | sc-201501 sc-201501A sc-201501B | 50 mg 100 mg 1 g | $163.00 $300.00 $1642.00 | 18 | |
By inhibiting calmodulin, these compounds can influence calcium signaling and potentially impact cadherin function. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Increases intracellular cAMP, which can modulate signaling pathways influencing cell adhesion dynamics. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
A tyrosine kinase inhibitor, which can alter signal transduction pathways related to cell adhesion and cadherin function. | ||||||