C2orf12 inhibitors would refer to a class of chemical compounds designed to interact with and inhibit the function of a protein encoded by the human gene C2orf12, where C2orf denotes chromosome 2 open reading frame 12. Genes labeled as open reading frames (orfs) are sequences of DNA that have the potential to be transcribed and translated into proteins but for which the function is not well characterized. The numerical designation provides information about the gene's location, in this case, chromosome 2. The gene product of C2orf12, if it is indeed a protein-coding gene, would have a specific function within the cell, which might be of interest to researchers for cellular or biochemical studies.
If substantial interest existed in the biological activity of the C2orf12 protein, the first step towards the development of C2orf12 inhibitors would be to gain a comprehensive understanding of the protein's structure, function, and its role within the cell. This would involve a variety of biochemical and molecular biology techniques to study the protein's expression patterns, subcellular localization, and interaction with other cellular components. Structural studies, potentially including methods like X-ray crystallography or cryo-electron microscopy, could provide a detailed view of the protein at the atomic level, revealing potential sites that could be targeted by small molecule inhibitors. For example, if C2orf12 were found to possess enzymatic activity, researchers would focus on its active site where substrate binding and reaction catalysis occur. Alternatively, if C2orf12 were part of a protein complex, the interface between the proteins could present a viable target for inhibition.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
Binds to DNA and inhibits RNA polymerase, leading to decreased RNA synthesis including that of RBMS1. | ||||||
α-Amanitin | 23109-05-9 | sc-202440 sc-202440A | 1 mg 5 mg | $260.00 $1029.00 | 26 | |
Inhibits RNA polymerase II, which is essential for mRNA synthesis, potentially reducing RBMS1 levels. | ||||||
Triptolide | 38748-32-2 | sc-200122 sc-200122A | 1 mg 5 mg | $88.00 $200.00 | 13 | |
Known to inhibit transcription by targeting RNA polymerase II, could reduce RBMS1 mRNA levels. | ||||||
Cordycepin | 73-03-0 | sc-203902 | 10 mg | $99.00 | 5 | |
A nucleoside analog that can terminate mRNA elongation, potentially affecting RBMS1 mRNA stability. | ||||||
DRB | 53-85-0 | sc-200581 sc-200581A sc-200581B sc-200581C | 10 mg 50 mg 100 mg 250 mg | $42.00 $185.00 $310.00 $650.00 | 6 | |
Inhibits RNA synthesis by targeting RNA polymerase II, potentially decreasing RBMS1 expression. | ||||||
Leptomycin B | 87081-35-4 | sc-358688 sc-358688A sc-358688B | 50 µg 500 µg 2.5 mg | $105.00 $408.00 $1224.00 | 35 | |
Inhibits nuclear export of RNA, which could indirectly reduce the translation of RBMS1 mRNA. | ||||||
Flavopiridol | 146426-40-6 | sc-202157 sc-202157A | 5 mg 25 mg | $78.00 $254.00 | 41 | |
A cyclin-dependent kinase inhibitor that can suppress transcription and thereby reduce RBMS1 levels. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
Binds to topoisomerase II, inhibiting its decatenation activity, which could affect transcription. | ||||||
1-β-D-Arabinofuranosylcytosine | 147-94-4 | sc-201628 sc-201628A sc-201628B sc-201628C sc-201628D | 1 g 5 g 25 g 100 g 250 g | $147.00 $258.00 $508.00 $717.00 $1432.00 | 1 | |
A nucleoside analog that inhibits DNA polymerase, potentially affecting the transcription of various genes. | ||||||
Homoharringtonine | 26833-87-4 | sc-202652 sc-202652A sc-202652B | 1 mg 5 mg 10 mg | $51.00 $123.00 $178.00 | 11 | |
Inhibits protein synthesis at the initiation step, possibly reducing overall protein levels including RBMS1. | ||||||