Nucleolar protein 4 like (NOL4L) is a protein that, as its name suggests, is closely related to nucleolar protein 4. The NOL4L protein is encoded by the NOL4L gene in humans. It is a nuclear protein that predominantly localizes to the nucleolus, a sub-nuclear compartment critically involved in ribosome biogenesis, stress response signaling, and various other cellular processes.
NOL4L is thought to function in the regulation of transcription and possibly in RNA processing, given its localization and the functions of other nucleolar proteins. The nucleolus is known for its role in the synthesis and maturation of ribosomal RNA (rRNA), along with the assembly of ribosomal subunits. Proteins localized to this region, such as NOL4L, are often implicated in these essential cellular activities or in the regulation of the cell cycle and proliferation due to their interactions with the nucleolar machinery.The specific functions of NOL4L are not as well characterized as those of some other nucleolar proteins, but it is thought to play a role in the maintenance of nucleolar architecture and integrity. NOL4L may also be involved in the cellular response to stress, as nucleolar proteins often participate in the regulation of the cell's response to environmental cues, including nutrient availability and cellular stress signals.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
Actinomycin D inhibits RNA polymerase, impacting ribosome biogenesis and potentially affecting NOL4L activity or expression. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Rapamycin inhibits mTOR, a key regulator of cell growth and proliferation, potentially influencing NOL4L through these pathways. | ||||||
Fluorouracil | 51-21-8 | sc-29060 sc-29060A | 1 g 5 g | $36.00 $149.00 | 11 | |
5-FU is a nucleotide analog that can disrupt RNA processing and may indirectly impact NOL4L activity. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic acid, involved in gene expression and cell differentiation, might indirectly affect NOL4L through its broad regulatory actions. | ||||||
Cisplatin | 15663-27-1 | sc-200896 sc-200896A | 100 mg 500 mg | $76.00 $216.00 | 101 | |
Cisplatin, a DNA-damaging agent, can induce cellular stress responses, potentially impacting NOL4L. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
TSA, an inhibitor of histone deacetylases, affects chromatin remodeling and gene expression, potentially influencing NOL4L. | ||||||
Nutlin-3 | 548472-68-0 | sc-45061 sc-45061A sc-45061B | 1 mg 5 mg 25 mg | $56.00 $212.00 $764.00 | 24 | |
Nutlin-3 disrupts p53-MDM2 interaction, potentially affecting cell cycle regulation and NOL4L activity. | ||||||
Leptomycin B | 87081-35-4 | sc-358688 sc-358688A sc-358688B | 50 µg 500 µg 2.5 mg | $105.00 $408.00 $1224.00 | 35 | |
Leptomycin B inhibits nuclear export, affecting nucleo-cytoplasmic transport, which could indirectly influence NOL4L. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $132.00 $1064.00 | 115 | |
Bortezomib inhibits proteasome activity, potentially affecting protein turnover and NOL4L regulation. | ||||||
Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $40.00 $82.00 $256.00 | 127 | |
Cycloheximide inhibits protein synthesis, potentially impacting cellular processes related to NOL4L. | ||||||