C19orf71 Inhibitors

ktin bundle interacting protein 1, known by the gene name TEKTIN4, is a protein that is presumed to play a role in the structural organization and function of cilia and flagella. Tektins are a family of filament-forming proteins that are key components of the axonemal microtubules in cilia and flagella, suggesting a crucial role for TEKTIN4 in motility and intracellular transport processes.

The specific interactions and functions of TEKTIN4 remain to be fully elucidated, but tektins in general are known to contribute to the stability and rigidity of axonemal microtubules and are thought to be involved in the bending of cilia and flagella. This is critical for the movement of cells, such as spermatozoa, and for the transport of fluids and particles across ciliated epithelial surfaces in various organs including the respiratory tract, reproductive system, and the ventricles of the brain.The "bundle interacting" aspect of TEKTIN4 implies that it may mediate interactions between tektin filaments or between tektins and other microtubule-associated proteins, which could be essential for the assembly and function of complex axonemal structures. Given the importance of ciliary function to a wide array of biological processes, TEKTIN4 could have roles in developmental biology, respiratory function, and reproductive health.