C11orf59 Activators
LAMTOR1 Activators refers to compounds that can modulate the activity or expression of LAMTOR1, a protein essential for amino acid sensing by Ragulator-Rag complex and mTORC1 activation. Compounds like Rapamycin, by inhibiting mTOR, can alter cellular pathways related to LAMTOR1, affecting its role in cell growth, proliferation, and survival. In a similar vein, Insulin, by initiating PI3K/AKT signaling, can influence cellular pathways that engage LAMTOR1. Furthermore, compounds such as Metformin and AICAR, which modulate cellular energy status and AMPK activity, can play a role in impacting processes where LAMTOR1 is pivotal. Resveratrol, known for SIRT1 activation and AMPK modulation, can influence LAMTOR1-related pathways, altering its functionality within cells.
Additionally, compounds like LY294002 and Wortmannin, acting as PI3K inhibitors, can modify cellular processes and pathways involving LAMTOR1. EGF, a potent activator of the EGFR/PI3K/AKT pathway, and IGF-1, known for insulin-like effects and AKT activation, can impact LAMTOR1 activity by influencing related cellular pathways. The alteration in the cellular environment by PD98059, a MEK inhibitor, and U0126, a potent inhibitor of MEK1/2, can also affect the role and activity of LAMTOR1 within cells.
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Items 1 to 10 of 23 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $74.00 $243.00 $731.00 $2572.00 $21848.00 | 53 | |
This compound intercalates into DNA, which could prevent transcription initiation of the C11orf59 gene by RNA polymerase, thereby downregulating its mRNA synthesis. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
May enhance LAMTOR1 activity by modulating cellular stress responses via its antioxidative properties. | ||||||
Triptolide | 38748-32-2 | sc-200122 sc-200122A | 1 mg 5 mg | $90.00 $204.00 | 13 | |
Triptolide may repress the transcriptional activity of RNA polymerase II, thus decreasing the production of C11orf59 transcripts. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Could modulate LAMTOR1 activity by impacting cellular proliferation and survival pathways, given its anti-inflammatory and antioxidant properties. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
May interact with LAMTOR1 by affecting cellular stress and survival pathways due to its antioxidative properties. | ||||||
DRB | 53-85-0 | sc-200581 sc-200581A sc-200581B sc-200581C | 10 mg 50 mg 100 mg 250 mg | $43.00 $189.00 $316.00 $663.00 | 6 | |
By inhibiting phosphorylation of RNA polymerase II, DRB might reduce the transcription elongation rate of genes, including C11orf59, leading to a decrease in its mRNA levels. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Could modulate LAMTOR1 through its anti-inflammatory and antioxidant effects, affecting cellular protective responses. | ||||||
α-Amanitin | 23109-05-9 | sc-202440 sc-202440A | 1 mg 5 mg | $269.00 $1050.00 | 26 | |
This toxin could specifically inhibit RNA polymerase II, resulting in a decreased synthesis of the C11orf59 mRNA transcript. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
May affect LAMTOR1 by modulating cellular stress responses, given its role in inducing phase 2 detox enzymes. | ||||||
Caffeic Acid | 331-39-5 | sc-200499 sc-200499A | 1 g 5 g | $32.00 $62.00 | 1 | |
Could interact with LAMTOR1 by affecting antioxidative stress pathways, impacting cellular protective responses. | ||||||