C11orf59 Activators
LAMTOR1 Activators refers to compounds that can modulate the activity or expression of LAMTOR1, a protein essential for amino acid sensing by Ragulator-Rag complex and mTORC1 activation. Compounds like Rapamycin, by inhibiting mTOR, can alter cellular pathways related to LAMTOR1, affecting its role in cell growth, proliferation, and survival. In a similar vein, Insulin, by initiating PI3K/AKT signaling, can influence cellular pathways that engage LAMTOR1. Furthermore, compounds such as Metformin and AICAR, which modulate cellular energy status and AMPK activity, can play a role in impacting processes where LAMTOR1 is pivotal. Resveratrol, known for SIRT1 activation and AMPK modulation, can influence LAMTOR1-related pathways, altering its functionality within cells.
Additionally, compounds like LY294002 and Wortmannin, acting as PI3K inhibitors, can modify cellular processes and pathways involving LAMTOR1. EGF, a potent activator of the EGFR/PI3K/AKT pathway, and IGF-1, known for insulin-like effects and AKT activation, can impact LAMTOR1 activity by influencing related cellular pathways. The alteration in the cellular environment by PD98059, a MEK inhibitor, and U0126, a potent inhibitor of MEK1/2, can also affect the role and activity of LAMTOR1 within cells.
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Items 11 to 20 of 23 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Flavopiridol | 146426-40-6 | sc-202157 sc-202157A | 5 mg 25 mg | $78.00 $259.00 | 41 | |
Flavopiridol may inhibit CDK9, a key factor in RNA polymerase II transcriptional elongation, which could lead to reduced levels of C11orf59 mRNA. | ||||||
Ferulic acid | 1135-24-6 | sc-204753 sc-204753A sc-204753B sc-204753C sc-204753D | 5 g 25 g 100 g 500 g 1 kg | $43.00 $63.00 $156.00 $563.00 $1008.00 | 10 | |
May modulate LAMTOR1 by affecting cellular antioxidative responses, given its antioxidant properties. | ||||||
CX-5461 | 1138549-36-6 | sc-507275 | 5 mg | $245.00 | ||
By selectively inhibiting RNA polymerase I, CX-5461 could indirectly lower the expression of C11orf59 by hampering ribosomal RNA synthesis and thereby protein translation capacity. | ||||||
Luteolin | 491-70-3 | sc-203119 sc-203119A sc-203119B sc-203119C sc-203119D | 5 mg 50 mg 500 mg 5 g 500 g | $27.00 $51.00 $101.00 $153.00 $1925.00 | 40 | |
Could interact with LAMTOR1 through its anti-inflammatory and antioxidative effects, modulating cellular protective responses. | ||||||
(±)-JQ1 | 1268524-69-1 | sc-472932 sc-472932A | 5 mg 25 mg | $231.00 $863.00 | 1 | |
JQ1 could displace BET bromodomain proteins from chromatin, leading to a reduced transcription of downstream genes such as C11orf59. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
May modulate LAMTOR1 by impacting cellular proliferation and survival, given its role as a phytoestrogen with antioxidative properties. | ||||||
Cordycepin | 73-03-0 | sc-203902 | 10 mg | $101.00 | 5 | |
This adenosine analog may interrupt the elongation process of C11orf59 mRNA transcription, leading to a decrease in full-length mRNA and subsequent protein synthesis. | ||||||
Kaempferol | 520-18-3 | sc-202679 sc-202679A sc-202679B | 25 mg 100 mg 1 g | $99.00 $216.00 $510.00 | 11 | |
Could enhance LAMTOR1 activity by modulating cellular protective responses through its antioxidative properties. | ||||||
Homoharringtonine | 26833-87-4 | sc-202652 sc-202652A sc-202652B | 1 mg 5 mg 10 mg | $52.00 $125.00 $182.00 | 11 | |
It may inhibit the initiation phase of translation, resulting in a reduced synthesis of the C11orf59 protein. | ||||||
Myricetin | 529-44-2 | sc-203147 sc-203147A sc-203147B sc-203147C sc-203147D | 25 mg 100 mg 1 g 25 g 100 g | $97.00 $188.00 $260.00 $510.00 $1022.00 | 3 | |
May interact with LAMTOR1 by modulating cellular antioxidative responses, given its antioxidant and anti-inflammatory properties. | ||||||