Date published: 2026-1-10

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c-Myc Activators

c-Myc activators, belonging to a distinctive chemical class, are compounds that possess the unique ability to stimulate the activity of the c-Myc gene, a critical regulator of cellular processes. These activators function by binding to specific sites within the promoter region of the c-Myc gene, facilitating its transcription and subsequent protein production. This class of compounds plays a pivotal role in molecular biology and cellular research as it provides researchers with valuable tools to manipulate the expression of c-Myc, offering insights into its normal functions and aberrations in various diseases.

The activation of the c-Myc gene by these compounds is a fascinating phenomenon, as c-Myc is involved in a multitude of cellular processes, including cell growth, proliferation, and differentiation. By enhancing the expression of c-Myc, these activators enable scientists to better understand the intricate web of molecular interactions in which c-Myc is implicated. This knowledge is fundamental for unraveling the mechanisms underlying conditions such as cancer, where dysregulation of c-Myc is frequently observed. Researchers can use c-Myc activators in a controlled laboratory setting to explore the intricate molecular pathways governed by this gene, shedding light on its role in both normal physiology and disease pathogenesis.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Bortezomib

179324-69-7sc-217785
sc-217785A
2.5 mg
25 mg
$135.00
$1085.00
115
(2)

Bortezomib increases the stability of c-Myc protein by blocking its degradation via the ubiquitin-proteasome pathway, leading to an accumulation of c-Myc in cells.

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$152.00
$479.00
$632.00
$1223.00
$2132.00
33
(3)

TSA can increase the acetylation of histones associated with c-Myc target genes, leading to enhanced gene expression and activity of c-Myc.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$63.00
$158.00
$326.00
233
(4)

Rapamycin indirectly affects c-Myc by inhibiting the mTOR pathway. mTOR activation can lead to increased c-Myc expression, so inhibiting mTOR with rapamycin can reduce c-Myc levels.