c-Myc activators, belonging to a distinctive chemical class, are compounds that possess the unique ability to stimulate the activity of the c-Myc gene, a critical regulator of cellular processes. These activators function by binding to specific sites within the promoter region of the c-Myc gene, facilitating its transcription and subsequent protein production. This class of compounds plays a pivotal role in molecular biology and cellular research as it provides researchers with valuable tools to manipulate the expression of c-Myc, offering insights into its normal functions and aberrations in various diseases.
The activation of the c-Myc gene by these compounds is a fascinating phenomenon, as c-Myc is involved in a multitude of cellular processes, including cell growth, proliferation, and differentiation. By enhancing the expression of c-Myc, these activators enable scientists to better understand the intricate web of molecular interactions in which c-Myc is implicated. This knowledge is fundamental for unraveling the mechanisms underlying conditions such as cancer, where dysregulation of c-Myc is frequently observed. Researchers can use c-Myc activators in a controlled laboratory setting to explore the intricate molecular pathways governed by this gene, shedding light on its role in both normal physiology and disease pathogenesis.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $135.00 $1085.00 | 115 | |
Bortezomib increases the stability of c-Myc protein by blocking its degradation via the ubiquitin-proteasome pathway, leading to an accumulation of c-Myc in cells. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
TSA can increase the acetylation of histones associated with c-Myc target genes, leading to enhanced gene expression and activity of c-Myc. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Rapamycin indirectly affects c-Myc by inhibiting the mTOR pathway. mTOR activation can lead to increased c-Myc expression, so inhibiting mTOR with rapamycin can reduce c-Myc levels. | ||||||