Brucella abortus Activators

These antibiotics work through various mechanisms to inhibit the growth and replication of the bacteria. Tetracyclines like Doxycycline and Tetracycline inhibit bacterial protein synthesis by binding to the 30S ribosomal subunit. Rifampin works by binding to the bacterial RNA polymerase, inhibiting RNA synthesis. Aminoglycosides such as Streptomycin and Gentamicin also target protein synthesis by binding to the 30S ribosomal subunit but with a slightly different mechanism compared to tetracyclines.

Fluoroquinolones, including Ciprofloxacin and Levofloxacin, target bacterial DNA gyrase, preventing DNA replication and transcription. Macrolides like Azithromycin and Erythromycin inhibit protein synthesis by binding to the 50S ribosomal subunit. Co-trimoxazole, a combination of Trimethoprim and Sulfamethoxazole, works synergistically to inhibit bacterial folate synthesis, which is essential for DNA and RNA synthesis.