Gentamicin sulfate CAS: 1405-41-0
MF: C21H43N5O7•H2SO4
MW: 575.67

Gentamicin sulfate (CAS 1405-41-0)

Gentamicin sulfate | CAS 1405-41-0 is rated 5.0 out of 5 by 1.
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Alternate Names: Gentamicin sulfate also known as Alcomicin; Bristagen; Cidomycin; Duragentam; Garamycin; Garasol; Genoptic; Gentacidin; Gentacin; Gentaglyde; Gentalyn; Gentamicin C Complex Citrate; Gentibioptal; Genticin; Gentocin; Gentogram; Gent-Ophtal; Getalline; GM Sulfate
Application: Gentamicin sulfate is a useful broad-spectrum cell culture antibiotic which inhibits protein synthesis
CAS Number: 1405-41-0
Molecular Weight: 575.67
Molecular Formula: C21H43N5O7•H2SO4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

Gentamycin Sulfate is a broad-spectrum, aminoglycoside antibiotic used for cell culture which inhibits protein synthesis in sensitive organisms. Gentamicin sulfate inhibits protein synthesis by binding to L6 protein and 50S ribosomal subunit. Gentamicin sulfate is reported to have activity against gram-negative bacteria, Pseudomonas aeruginosa, gram-positive Staphylococcus aureus and some mycoplasmas. Gentamicin sulfate is reported to have low toxicity to mammalian cells and viruses at certain concentrations, and Gentamicin sulfate is useful for long-term tissue culture studies with viruses. This compound is a mixture of Gentamycin c1, c1a and c2.


References

1. Martin, N.L., et al 1986. Antimicrob. Agents Chemother. 29: 1079-1087. PMID: 2425732

2. Kadurugamuwa, J.L., et al. 1993. J. Bacteriol. 175(: 5798-5805. PMID: 8376327

3. Montenez, J.P., et al. 1994. Toxicol. Lett. 73: 201-208. PMID: 8091428

Formulation :
a mixture of 3 major components, Gentamicin C1, C1a and C2
Appearance :
Powder
Physical State :
Solid
Solubility :
Soluble in water (115 mg/ml at 25° C), DMSO (<1 mg/ml at 25° C), and ethanol (<1 mg/ml at 25° C).
Storage :
Store at 4° C
Refractive Index :
n20D 1.58 (Predicted)
Optical Activity :
α20D 102
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
MDL Number :
MFCD00270181
EC Number :
215-778-9
SMILES :
CC(C1CCC(C(O1)OC2C(CC(C(C2O)OC3C(C(C(CO3)(C)O)NC)O)N)N)N)NC.OS(=O)(=O)O

Download SDS (MSDS)

Certificate of Analysis

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Gentamicin sulfate (CAS 1405-41-0)  Product Citations

See how others have used Gentamicin sulfate (CAS 1405-41-0). Click on the entry to view the PubMed entry .

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PMID: # 30156610  Coutinho, AGG.|Biscaia, SMP.|Fernandez, R.|Tararthuch, AL.| et al. 2018. Braz. J. Med. Biol. Res. 51: e7417.

Citations 1 to 1 of 1 total
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Rated 5 out of 5 by from Various publications cite the use of Gentamicin Various publications cite the use of Gentamicin sulfate, a broad-spectrum, aminoglycoside antibiotic, in cell cultures to inhibit protein synthesis in sensitive organisms. -SCBT Publication Review
Date published: 2015-04-07
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