Molecular structure of Levofloxacin, CAS Number: 100986-85-4
Levofloxacin (CAS 100986-85-4)
See product citations (3)
Alternate Names:
(−)-Ofloxacin
Application:
Levofloxacin is an antibiotic compound
CAS Number:
100986-85-4
Purity:
≥98%
Molecular Weight:
361.37
Molecular Formula:
C18H20FN3O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Levofloxacin is a compound that is extensively studied in the field of microbiology and biochemistry for its interaction with bacterial enzymes and its role in inhibiting bacterial DNA replication processes. It is used as a reference compound in research focused on understanding bacterial resistance mechanisms, where it can provide insights into the genetic mutations and adaptive responses of bacteria. Additionally, Levofloxacin is involved in studies of bacterial gyrase and topoisomerase IV, enzymes that are for DNA supercoiling and maintenance. The compound′s effectiveness in binding to these enzymes and disrupting their function makes it useful for investigating the intricacies of bacterial DNA replication and transcription.
Levofloxacin (CAS 100986-85-4) References
- Levofloxacin and indolicidin for combination antimicrobial therapy. | Ghaffar, KA., et al. 2015. Curr Drug Deliv. 12: 108-14. PMID: 25213074
- Levofloxacin versus azithromycin for treating legionella pneumonia: a propensity score analysis. | Garcia-Vidal, C., et al. 2017. Clin Microbiol Infect. 23: 653-658. PMID: 28267637
- Levofloxacin Pharmacokinetics/Pharmacodynamics, Dosing, Susceptibility Breakpoints, and Artificial Intelligence in the Treatment of Multidrug-resistant Tuberculosis. | Deshpande, D., et al. 2018. Clin Infect Dis. 67: S293-S302. PMID: 30496461
- Levofloxacin-associated Encephalopathy with Severe Hyperventilation. | Sugiura, M., et al. 2019. Intern Med. 58: 1495-1499. PMID: 30713304
- The effect of levofloxacin on the lung microbiota of laboratory rats. | Finn, SMB., et al. 2019. Exp Lung Res. 45: 200-208. PMID: 31298956
- Adverse effects of levofloxacin and oxytetracycline on aquatic microbial communities. | Zhou, Z., et al. 2020. Sci Total Environ. 734: 139499. PMID: 32464375
- Acute pancreatitis associated with levofloxacin. | Jiménez Moreno, MA., et al. 2020. Rev Esp Enferm Dig. 112: 510. PMID: 32496110
- Levofloxacin-loaded naturally occurring monoterpene-based nanoemulgel: a feasible efficient system to circumvent MRSA ocular infections. | Mehanna, MM., et al. 2020. Drug Dev Ind Pharm. 46: 1787-1799. PMID: 32896171
- Urine colorimetry for levofloxacin pharmacokinetics and personalized dosing in people with drug-resistant tuberculosis. | Rao, P., et al. 2020. Int J Mycobacteriol. 9: 411-416. PMID: 33323657
- Synergistic antibacterial effect of graphene-coated titanium loaded with levofloxacin. | Sun, J., et al. 2021. Colloids Surf B Biointerfaces. 208: 112090. PMID: 34507071
- Levofloxacin pharmacodynamics against Stenotrophomonas maltophilia in a neutropenic murine thigh infection model: implications for susceptibility breakpoint revision. | Fratoni, AJ., et al. 2021. J Antimicrob Chemother. 77: 164-168. PMID: 34542637
- A systematic review and meta-analysis of levofloxacin and ciprofloxacin in the treatment of urinary tract infection. | Xue, Z., et al. 2021. Ann Palliat Med. 10: 9765-9771. PMID: 34628902
- Adsorption of levofloxacin on natural zeolite: effects of ammonia nitrogen and humic acid. | Chi, X., et al. 2022. Water Sci Technol. 85: 2928-2944. PMID: 35638797
- Activity of Delafloxacin and Levofloxacin against Stenotrophomonas maltophilia at Simulated Plasma and Intrapulmonary pH Values. | Vialichka, A., et al. 2022. Microbiol Spectr. 10: e0270521. PMID: 35862943
Inhibitor of:
AMDHD1, Bacillus anthracis spore antigen, Borrelia burgdorferi Osp A, C. trachomatis, Chlamydia LPS, CNF2, COPT2, CRS1C-3, CRS4C-5, cryptdin 22, cryptdin 3, E. coli, GRAMD2, H. influenzae B, Legionella pneumophila LPS, Mycobacterium avium, Streptococcus agalactiae, Streptococcus Group B, and Topo II.Activator of:
Brucella abortus, CagA, Ciprofloxacin, MT 38 kDa antigen, OCTN1, Salmonella paratyphi 0-2, and SLC6A19.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Levofloxacin, 10 mg | sc-252953 | 10 mg | $39.00 | |||
Levofloxacin, 250 mg | sc-252953B | 250 mg | $45.00 | |||
Levofloxacin, 1 g | sc-252953A | 1 g | $53.00 |