Brucella abortus Antibody (BrG11): sc-66117
- Brucella abortus Antibody (BrG11) is a mouse monoclonal IgG2a provided at 100 µg/ml
- raised against crude Brucella abortus cell lysate
- recommended for detection of intact Brucella cells of Brucella abortus origin by WB
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Brucella abortus Antibody (BrG11). This work is in progress.
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Brucella abortus Antibody (BrG11) is a mouse monoclonal IgG2a antibody that detects Brucella abortus with species reactivity specific to Brucella abortus by western blotting (WB). Brucella abortus is a significant pathogen responsible for bovine brucellosis, which can lead to severe reproductive issues in cattle, including spontaneous abortion and infertility. This bacterium primarily infects the placenta and fetus of gestating cows, posing a risk not only to livestock but also to humans, who can contract the infection through unpasteurized milk or contact with infected animals. Brucella abortus plays a crucial role in the organism′s virulence, utilizing cyclic β-1,2-glucan to adapt to hypo-osmotic environments, which is vital for survival in both natural and host settings. Additionally, to combat iron deprivation, a common challenge faced by Brucella abortus, the bacterium secretes siderophores such as 2,3-dihydroxybenzoic acid and brucebactin, regulated by IRR. The ability of Brucella abortus to effectively manage these environmental stresses underscores its pathogenicity and highlights the importance of anti-Brucella abortus antibody (BrG11) in research and diagnostic applications.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Brucella abortus Antibody (BrG11) | sc-66117 | 100 µg/ml | $322.00 |