Date published: 2025-12-18

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Brn CRISPR Plasmids

Santa Cruz Biotechnology, Inc. offers a broad range of gene editing products including CRISPR/Cas9 Knockout and CRISPR Double Nickase plasmids for gene silencing. Brn gene silencers are available as Brn CRISPR/Cas9 Knockout plasmids and Brn Double Nickase Plasmids. Brn CRISPR/dCas9 Activation Plasmids and CRISPR Lenti Activation Systems for gene activation are also available. Gene silencers and activators are useful for gene studies in combination with antibodies used for protein detection.

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Brn CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Brn-1/BRN1/POU3F3 CRISPR/Cas9 KO Plasmid (h)

sc-410950hGene KnockoutGFP0
(0)

Brn-1/BRN1/POU3F3 HDR Plasmid (h)

sc-410950-HDRhHomology Directed RepairPuromycin0
(0)

Brn-1/BRN1/POU3F3 Double Nickase Plasmid (h)

sc-410950-NIChGene KnockoutPuromycin0
(0)

Brn-1/BRN1/POU3F3 Double Nickase Plasmid (h2)

sc-410950-NIC-2hGene KnockoutPuromycin0
(0)

Brn-1/BRN1/POU3F3 CRISPR/Cas9 KO Plasmid (m)

sc-422352mGene KnockoutGFP0
(0)

Brn-1/BRN1/POU3F3 HDR Plasmid (m)

sc-422352-HDRmHomology Directed RepairPuromycin0
(0)

Brn-1/BRN1/POU3F3 Double Nickase Plasmid (m)

sc-422352-NICmGene KnockoutPuromycin0
(0)

Brn-1/BRN1/POU3F3 Double Nickase Plasmid (m2)

sc-422352-NIC-2mGene KnockoutPuromycin0
(0)

Brn-2/BRN2/POU3F2 CRISPR/Cas9 KO Plasmid (h)

sc-400392hGene KnockoutGFP0
(0)

Brn-2/BRN2/POU3F2 CRISPR/Cas9 KO Plasmid (h2)

sc-400392-KO-2hGene KnockoutGFP0
(0)

Brn-2/BRN2/POU3F2 HDR Plasmid (h2)

sc-400392-HDR-2hHomology Directed RepairPuromycin0
(0)

Brn-2/BRN2/POU3F2 Double Nickase Plasmid (h)

sc-400392-NIChGene KnockoutPuromycin0
(0)

Brn-2/BRN2/POU3F2 Double Nickase Plasmid (h2)

sc-400392-NIC-2hGene KnockoutPuromycin0
(0)

Brn-2/BRN2/POU3F2 CRISPR/Cas9 KO Plasmid (m)

sc-422351mGene KnockoutGFP0
(0)

Brn-2/BRN2/POU3F2 HDR Plasmid (m)

sc-422351-HDRmHomology Directed RepairPuromycin0
(0)

Brn-2/BRN2/POU3F2 Double Nickase Plasmid (m)

sc-422351-NICmGene KnockoutPuromycin0
(0)

Brn-2/BRN2/POU3F2 Double Nickase Plasmid (m2)

sc-422351-NIC-2mGene KnockoutPuromycin0
(0)

Brn-3a/BRN3A/POU4F1 CRISPR/Cas9 KO Plasmid (h2)

sc-400322-KO-2hGene KnockoutGFP0
(0)

Brn-3a/BRN3A/POU4F1 HDR Plasmid (h2)

sc-400322-HDR-2hHomology Directed RepairPuromycin0
(0)

Brn-3a/BRN3A/POU4F1 Double Nickase Plasmid (h)

sc-400322-NIChGene KnockoutPuromycin0
(0)

Brn-3a/BRN3A/POU4F1 Double Nickase Plasmid (h2)

sc-400322-NIC-2hGene KnockoutPuromycin0
(0)

Brn-3a/BRN3A/POU4F1 CRISPR/Cas9 KO Plasmid (m)

sc-422354mGene KnockoutGFP0
(0)

Brn-3a/BRN3A/POU4F1 HDR Plasmid (m)

sc-422354-HDRmHomology Directed RepairPuromycin0
(0)

Brn-3a/BRN3A/POU4F1 Double Nickase Plasmid (m)

sc-422354-NICmGene KnockoutPuromycin0
(0)

Brn-3a/BRN3A/POU4F1 Double Nickase Plasmid (m2)

sc-422354-NIC-2mGene KnockoutPuromycin0
(0)

Brn-3b/BRN3B/POU4F2 CRISPR/Cas9 KO Plasmid (h)

sc-400382hGene KnockoutGFP0
(0)

Brn-3b/BRN3B/POU4F2 Double Nickase Plasmid (h)

sc-400382-NIChGene KnockoutPuromycin0
(0)

Brn-3b/BRN3B/POU4F2 Double Nickase Plasmid (h2)

sc-400382-NIC-2hGene KnockoutPuromycin0
(0)

Brn-3b/BRN3B/POU4F2 CRISPR/Cas9 KO Plasmid (m)

sc-422355mGene KnockoutGFP0
(0)

Brn-3b/BRN3B/POU4F2 HDR Plasmid (m)

sc-422355-HDRmHomology Directed RepairPuromycin0
(0)

Brn-3b/BRN3B/POU4F2 Double Nickase Plasmid (m)

sc-422355-NICmGene KnockoutPuromycin0
(0)

Brn-3b/BRN3B/POU4F2 Double Nickase Plasmid (m2)

sc-422355-NIC-2mGene KnockoutPuromycin0
(0)

Brn-3c/BRN3C/POU4F3 CRISPR/Cas9 KO Plasmid (h)

sc-401701hGene KnockoutGFP0
(0)

Brn-3c/BRN3C/POU4F3 HDR Plasmid (h)

sc-401701-HDRhHomology Directed RepairPuromycin0
(0)

Brn-3c/BRN3C/POU4F3 Double Nickase Plasmid (h)

sc-401701-NIChGene KnockoutPuromycin0
(0)

Brn-3c/BRN3C/POU4F3 Double Nickase Plasmid (h2)

sc-401701-NIC-2hGene KnockoutPuromycin0
(0)

Brn-3c/BRN3C/POU4F3 CRISPR/Cas9 KO Plasmid (m)

sc-422356mGene KnockoutGFP0
(0)

Brn-3c/BRN3C/POU4F3 HDR Plasmid (m)

sc-422356-HDRmHomology Directed RepairPuromycin0
(0)

Brn-3c/BRN3C/POU4F3 Double Nickase Plasmid (m)

sc-422356-NICmGene KnockoutPuromycin0
(0)

Brn-3c/BRN3C/POU4F3 Double Nickase Plasmid (m2)

sc-422356-NIC-2mGene KnockoutPuromycin0
(0)

Brn-5/BRN5/POU6F1 CRISPR/Cas9 KO Plasmid (h)

sc-409474hGene KnockoutGFP0
(0)

Brn-5/BRN5/POU6F1 HDR Plasmid (h)

sc-409474-HDRhHomology Directed RepairPuromycin0
(0)

Brn-5/BRN5/POU6F1 Double Nickase Plasmid (h)

sc-409474-NIChGene KnockoutPuromycin0
(0)

Brn-5/BRN5/POU6F1 Double Nickase Plasmid (h2)

sc-409474-NIC-2hGene KnockoutPuromycin0
(0)

Brn-5/BRN5/POU6F1 CRISPR/Cas9 KO Plasmid (m)

sc-422358mGene KnockoutGFP0
(0)

Brn-5/BRN5/POU6F1 HDR Plasmid (m)

sc-422358-HDRmHomology Directed RepairPuromycin0
(0)

Brn-5/BRN5/POU6F1 Double Nickase Plasmid (m)

sc-422358-NICmGene KnockoutPuromycin0
(0)

Brn-5/BRN5/POU6F1 Double Nickase Plasmid (m2)

sc-422358-NIC-2mGene KnockoutPuromycin0
(0)

Brn CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Brn-1/BRN1/POU3F3 CRISPR Activation Plasmid (h)

sc-410950-ACThGene ActivationPuro, Blast, Hygro0
(0)

Brn-1/BRN1/POU3F3 CRISPR Activation Plasmid (h2)

sc-410950-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

Brn-1/BRN1/POU3F3 Lentiviral Activation Particles (h)

sc-410950-LAChGene ActivationPuro, Blast, Hygro0
(0)

Brn-1/BRN1/POU3F3 Lentiviral Activation Particles (h2)

sc-410950-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

Brn-1/BRN1/POU3F3 CRISPR Activation Plasmid (m)

sc-422352-ACTmGene ActivationPuro, Blast, Hygro0
(0)

Brn-1/BRN1/POU3F3 CRISPR Activation Plasmid (m2)

sc-422352-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

Brn-1/BRN1/POU3F3 Lentiviral Activation Particles (m)

sc-422352-LACmGene ActivationPuro, Blast, Hygro0
(0)

Brn-1/BRN1/POU3F3 Lentiviral Activation Particles (m2)

sc-422352-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

Brn-2/BRN2/POU3F2 CRISPR Activation Plasmid (h)

sc-400392-ACThGene ActivationPuro, Blast, Hygro0
(0)

Brn-2/BRN2/POU3F2 CRISPR Activation Plasmid (h2)

sc-400392-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

Brn-2/BRN2/POU3F2 Lentiviral Activation Particles (h)

sc-400392-LAChGene ActivationPuro, Blast, Hygro0
(0)

Brn-2/BRN2/POU3F2 Lentiviral Activation Particles (h2)

sc-400392-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

Brn-2/BRN2/POU3F2 CRISPR Activation Plasmid (m)

sc-422351-ACTmGene ActivationPuro, Blast, Hygro0
(0)

Brn-2/BRN2/POU3F2 CRISPR Activation Plasmid (m2)

sc-422351-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

Brn-2/BRN2/POU3F2 Lentiviral Activation Particles (m)

sc-422351-LACmGene ActivationPuro, Blast, Hygro0
(0)

Brn-2/BRN2/POU3F2 Lentiviral Activation Particles (m2)

sc-422351-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

Brn-3a/BRN3A/POU4F1 CRISPR Activation Plasmid (h)

sc-400322-ACThGene ActivationPuro, Blast, Hygro0
(0)

Brn-3a/BRN3A/POU4F1 CRISPR Activation Plasmid (h2)

sc-400322-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

Brn-3a/BRN3A/POU4F1 Lentiviral Activation Particles (h)

sc-400322-LAChGene ActivationPuro, Blast, Hygro0
(0)

Brn-3a/BRN3A/POU4F1 Lentiviral Activation Particles (h2)

sc-400322-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

Brn-3a/BRN3A/POU4F1 CRISPR Activation Plasmid (m)

sc-422354-ACTmGene ActivationPuro, Blast, Hygro0
(0)

Brn-3a/BRN3A/POU4F1 CRISPR Activation Plasmid (m2)

sc-422354-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

Brn-3a/BRN3A/POU4F1 Lentiviral Activation Particles (m)

sc-422354-LACmGene ActivationPuro, Blast, Hygro0
(0)

Brn-3a/BRN3A/POU4F1 Lentiviral Activation Particles (m2)

sc-422354-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

Brn-3b/BRN3B/POU4F2 CRISPR Activation Plasmid (h)

sc-400382-ACThGene ActivationPuro, Blast, Hygro0
(0)

Brn-3b/BRN3B/POU4F2 CRISPR Activation Plasmid (h2)

sc-400382-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

Brn-3b/BRN3B/POU4F2 Lentiviral Activation Particles (h)

sc-400382-LAChGene ActivationPuro, Blast, Hygro0
(0)

Brn-3b/BRN3B/POU4F2 Lentiviral Activation Particles (h2)

sc-400382-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

Brn-3b/BRN3B/POU4F2 CRISPR Activation Plasmid (m)

sc-422355-ACTmGene ActivationPuro, Blast, Hygro0
(0)

Brn-3b/BRN3B/POU4F2 CRISPR Activation Plasmid (m2)

sc-422355-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

Brn-3b/BRN3B/POU4F2 Lentiviral Activation Particles (m)

sc-422355-LACmGene ActivationPuro, Blast, Hygro0
(0)

Brn-3b/BRN3B/POU4F2 Lentiviral Activation Particles (m2)

sc-422355-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

Brn-3c/BRN3C/POU4F3 CRISPR Activation Plasmid (h)

sc-401701-ACThGene ActivationPuro, Blast, Hygro0
(0)

Brn-3c/BRN3C/POU4F3 CRISPR Activation Plasmid (h2)

sc-401701-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

Brn-3c/BRN3C/POU4F3 Lentiviral Activation Particles (h)

sc-401701-LAChGene ActivationPuro, Blast, Hygro0
(0)

Brn-3c/BRN3C/POU4F3 Lentiviral Activation Particles (h2)

sc-401701-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

Brn-3c/BRN3C/POU4F3 CRISPR Activation Plasmid (m)

sc-422356-ACTmGene ActivationPuro, Blast, Hygro0
(0)

Brn-3c/BRN3C/POU4F3 CRISPR Activation Plasmid (m2)

sc-422356-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

Brn-3c/BRN3C/POU4F3 Lentiviral Activation Particles (m)

sc-422356-LACmGene ActivationPuro, Blast, Hygro0
(0)

Brn-3c/BRN3C/POU4F3 Lentiviral Activation Particles (m2)

sc-422356-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

Brn-5/BRN5/POU6F1 CRISPR Activation Plasmid (h)

sc-409474-ACThGene ActivationPuro, Blast, Hygro0
(0)

Brn-5/BRN5/POU6F1 CRISPR Activation Plasmid (h2)

sc-409474-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

Brn-5/BRN5/POU6F1 Lentiviral Activation Particles (h)

sc-409474-LAChGene ActivationPuro, Blast, Hygro0
(0)

Brn-5/BRN5/POU6F1 Lentiviral Activation Particles (h2)

sc-409474-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

Brn-5/BRN5/POU6F1 CRISPR Activation Plasmid (m)

sc-422358-ACTmGene ActivationPuro, Blast, Hygro0
(0)

Brn-5/BRN5/POU6F1 CRISPR Activation Plasmid (m2)

sc-422358-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

Brn-5/BRN5/POU6F1 Lentiviral Activation Particles (m)

sc-422358-LACmGene ActivationPuro, Blast, Hygro0
(0)

Brn-5/BRN5/POU6F1 Lentiviral Activation Particles (m2)

sc-422358-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)