BMP2K Inhibitors
BMP2K inhibitors belong to a distinct chemical class characterized by their ability to modulate the activity of the BMP2K enzyme. This enzyme, also known as BMP2-inducible kinase, plays a significant role in cellular signaling pathways. BMP2K is involved in the regulation of various intracellular processes, including cell growth, differentiation, and gene expression. The inhibitors designed to target BMP2K exert their effects by specifically binding to the enzyme's active site or other relevant binding sites, leading to a disruption in its normal catalytic function.
This class of compounds has garnered attention due to its potential implications in influencing cellular responses and intracellular cascades mediated by BMP2K. Researchers are actively investigating the structural and functional properties of BMP2K inhibitors to better comprehend their mechanisms of action and their potential applications in cellular studies. By fine-tuning the interactions between these inhibitors and BMP2K, scientists aim to unravel novel insights into cellular signaling pathways and their intricate regulatory mechanisms.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
DMH-1 | 1206711-16-1 | sc-361171 sc-361171B sc-361171A sc-361171C | 10 mg 25 mg 50 mg 100 mg | $209.00 $312.00 $620.00 $1026.00 | 2 | |
DMH1 is a selective BMP2K inhibitor that has been used in research to study BMP signaling pathways. It was developed to specifically target BMP type I receptors, including BMP2K. | ||||||
4-(6-(4-(Piperazin-1-yl)phenyl)pyrazolo[1,5-a]pyrimidin-3-yl)quinoline | 1062368-24-4 | sc-476297 | 5 mg | $240.00 | ||
LDN-193189 is a potent and selective BMP receptor type I inhibitor, which includes BMP2K. It has been used in various studies to investigate BMP signaling and its implications in development and disease. | ||||||
K02288 | 1431985-92-0 | sc-488981 | 5 mg | $330.00 | ||
K02288 is another selective inhibitor of BMP type I receptors, including BMP2K. It has been used in research to explore the roles of BMP signaling in different biological processes. | ||||||
LDN-214117 | 1627503-67-6 | sc-507451 | 5 mg | $165.00 | ||
LDN-214117 is a small-molecule inhibitor that targets BMP receptors, including BMP2K. It has shown potential therapeutic applications in various contexts, including cancer and fibrosis. | ||||||
LDN 193719 | 1062368-49-3 | sc-489383 | 10 mg | $189.00 | ||
LDN 193719 is a chemical compound that inhibits BMP2K and has been used in research to better understand BMP signaling pathways and their roles in various cellular processes. | ||||||
5-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | 1432597-26-6 | sc-476318 | 5 mg | $380.00 | ||
LDN-212854 is a BMP type I receptor inhibitor that affects BMP2K activity. It has been studied for its potential to modulate BMP signaling and its downstream effects. | ||||||
IWR-1-endo | 1127442-82-3 | sc-295215 sc-295215A | 5 mg 10 mg | $82.00 $132.00 | 19 | |
While primarily known as a Wnt signaling inhibitor, IWR-1 has also been reported to inhibit BMP2K, among other kinases. It has been used in research to explore the crosstalk between different signaling pathways. | ||||||