Blimp-1 Inhibitors
Common Blimp-1 Inhibitors include, but are not limited to 1H-Imidazole-4-carboxamide CAS 26832-08-6, Triptolide CAS 38748-32-2, PRIMA-1MET CAS 5291-32-7, GSK-3 Inhibitor II CAS 478482-75-6 and Curcumin CAS 458-37-7.
Blimp-1 inhibitors belong to a chemical class designed to target the activity of the B lymphocyte-induced maturation protein 1 (Blimp-1), a transcription factor that plays a critical role in regulating the differentiation and function of various immune cells, particularly B cells and plasma cells. Blimp-1 is known for its ability to suppress the expression of genes associated with the maintenance of B cell identity, while promoting the development of plasma cells, which are specialized cells responsible for producing antibodies.
Inhibiting Blimp-1 activity can impact the immune response by altering the differentiation and function of B cells and plasma cells. By targeting this transcription factor, researchers aim to gain insights into the intricate regulatory networks that control immune cell development and function. This class of inhibitors is of significant interest in immunology research, as it provides a tool to better understand the mechanisms underlying immune responses, antibody production, and immune-related disorders. The study of Blimp-1 inhibitors contributes to advancing the knowledge of immune system regulation and the modulation of immune responses for various purposes.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
1H-Imidazole-4-carboxamide | 26832-08-6 | sc-273678 | 200 mg | $144.00 | ||
A potential BLIMP-1 inhibitor that might affect BLIMP-1's transcriptional activity, impacting immune responses. | ||||||
Triptolide | 38748-32-2 | sc-200122 sc-200122A | 1 mg 5 mg | $88.00 $200.00 | 13 | |
An inhibitor that could suppress BLIMP-1 expression, potentially affecting immune cell differentiation and function. | ||||||
PRIMA-1MET | 5291-32-7 | sc-361295 sc-361295A | 10 mg 25 mg | $150.00 $319.00 | 5 | |
Restores p53 activity and indirectly inhibits BLIMP-1 expression in certain contexts, modulating immune responses. | ||||||
GSK-3 Inhibitor II | 478482-75-6 | sc-24020 sc-24020A | 5 mg 25 mg | $80.00 $290.00 | 11 | |
Inhibitors of GSK-3 could potentially affect BLIMP-1 expression and immune cell differentiation. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
A natural compound that may suppress BLIMP-1 expression, potentially affecting immune cell differentiation and responses. | ||||||
Methylstat | 1310877-95-2 | sc-507374 | 10 mg | $480.00 | ||
A chemical that could inhibit BLIMP-1 transcriptional activity, potentially affecting immune cell differentiation. | ||||||
TGF-β RI Kinase Inhibitor V | 627536-09-8 | sc-203294 | 2 mg | $86.00 | 3 | |
A TGF-β receptor inhibitor that might indirectly affect BLIMP-1 expression and immune cell responses. | ||||||
Nobiletin | 478-01-3 | sc-202733 | 10 mg | $189.00 | 2 | |
A flavonoid with potential inhibitory effects on BLIMP-1 expression, impacting immune cell differentiation. | ||||||
C646 | 328968-36-1 | sc-364452 sc-364452A | 10 mg 50 mg | $260.00 $925.00 | 5 | |
A histone acetyltransferase inhibitor that could modulate BLIMP-1 expression and immune cell function. | ||||||
Tenovin-6 | 1011557-82-6 | sc-224296 sc-224296A | 1 mg 5 mg | $272.00 $1214.00 | 9 | |
Inhibits SIRT1, which might lead to the suppression of BLIMP-1 expression and modulation of immune responses. | ||||||