Bex3 Activators
Bex3 (Brain Expressed X-Linked 3), also known as NGFRAP1 (Nerve Growth Factor Receptor (TNFRSF16) Associated Protein 1), is a protein encoded by the BEX3 gene in humans. This protein is part of the Bex family of proteins, which are primarily expressed in the nervous system.Bex3 is known to interact with the p75 neurotrophin receptor (p75NTR), a receptor involved in regulating neuronal survival, neurite outgrowth, and apoptosis. Through this interaction, Bex3 can influence neuronal development and function. Additionally, Bex3 may play a role in intracellular signaling pathways, although the specifics of these roles are not yet fully understood.
Bex3 is ubiquitously expressed but predominantly found in tissues of the central nervous system. Its expression level can vary depending on cellular context and stimuli, suggesting that it may be involved in response to specific cellular conditions or stresses.Dysregulation of Bex3 has been linked to various pathological conditions. Overexpression of Bex3 has been observed in certain types of cancer, including gliomas and breast cancer, suggesting a potential role in tumorigenesis. Conversely, loss of Bex3 expression is associated with Alzheimer's disease, implying a role in neuronal health and function.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol, a polyphenolic compound found in grapes, has been shown to modulate apoptosis and could indirectly affect Bex3 activity. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
Sulforaphane, a compound in cruciferous vegetables, is known for its role in cellular protective mechanisms and may indirectly modulate Bex3. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin, a flavonoid found in many fruits and vegetables, has antioxidant properties and may affect apoptosis-related proteins like Bex3. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG, a major component of green tea, has been shown to influence apoptotic processes, possibly affecting Bex3. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $71.00 $163.00 $296.00 | 2 | |
Vitamin D3, besides its role in calcium homeostasis, has been implicated in the regulation of apoptosis. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $48.00 | ||
Zinc, an essential mineral, plays a role in various cellular processes, including apoptosis, and could impact Bex3 function. | ||||||
Selenium | 7782-49-2 | sc-250973 | 50 g | $62.00 | 1 | |
Selenium, a trace element, is known for its role in antioxidant defense systems and may affect proteins like Bex3. | ||||||
N-Acetyl-L-cysteine | 616-91-1 | sc-202232 sc-202232A sc-202232C sc-202232B | 5 g 25 g 1 kg 100 g | $34.00 $74.00 $270.00 $114.00 | 34 | |
NAC, a precursor to glutathione, has antioxidant properties and may modulate apoptotic pathways affecting Bex3. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium, commonly used in psychiatric, has been shown to influence several signaling pathways that could impact Bex3. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Rapamycin, an immunosuppressant, affects mTOR signaling and could indirectly influence Bex3 activity. | ||||||