Date published: 2025-10-6

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Bestrophin Antibodies

Santa Cruz Biotechnology features a diverse variety of Bestrophin monoclonal antibodies for investigating bestrophins in cellular processes. Bestrophin monoclonal antibodies are suitable for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Bestrophins are integral membrane proteins that play a crucial role in the regulation of ion channels and are primarily associated with the function of retinal pigment epithelium cells. Bestrophins contribute to various physiological processes, including the maintenance of ion homeostasis and the modulation of retinal signaling pathways. Dysregulation of bestrophin function has been linked to several retinal diseases, making research in this area particularly significant. Bestrophin monoclonal antibodies enable researchers to explore cellular localization, protein interactions, and expression patterns in different tissue types. Understanding bestrophin function and regulation can provide critical insights into retinal disease mechanisms and potential therapeutic approaches. Investigating bestrophin-related pathologies with Santa Cruz Biotechnology monoclonal antibodies supports advancement in vision research and contributes to the development of new therapeutic strategies.

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Bestrophin Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

Bestrophin Antibody (E6-6)

sc-32792mouse IgG1 κC-Terminal (h)WB, IP, IF, IHC(P)h
4
(3)

Bestrophin-2 Antibody (D-7)

sc-376351mouse IgG2b κ322-509 (h)WB, IP, IF, ELISAm, r, h

new

(1)

Bestrophin-2 Antibody (B-5)

sc-376660mouse IgG1 κ322-509 (h)WB, IP, IF, ELISAm, r, h

new

(2)

Bestrophin CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Bestrophin CRISPR/Cas9 KO Plasmid (h)

sc-404183hGene KnockoutGFP0
(0)

Bestrophin HDR Plasmid (h)

sc-404183-HDRhHomology Directed RepairPuromycin0
(0)

Bestrophin Double Nickase Plasmid (h)

sc-404183-NIChGene KnockoutPuromycin0
(0)

Bestrophin Double Nickase Plasmid (h2)

sc-404183-NIC-2hGene KnockoutPuromycin0
(0)

Bestrophin CRISPR/Cas9 KO Plasmid (m)

sc-423991mGene KnockoutGFP0
(0)

Bestrophin HDR Plasmid (m)

sc-423991-HDRmHomology Directed RepairPuromycin0
(0)

Bestrophin Double Nickase Plasmid (m)

sc-423991-NICmGene KnockoutPuromycin0
(0)

Bestrophin Double Nickase Plasmid (m2)

sc-423991-NIC-2mGene KnockoutPuromycin0
(0)

Bestrophin-2 CRISPR/Cas9 KO Plasmid (h)

sc-412345hGene KnockoutGFP0
(0)

Bestrophin-2 HDR Plasmid (h)

sc-412345-HDRhHomology Directed RepairPuromycin0
(0)

Bestrophin-2 Double Nickase Plasmid (h)

sc-412345-NIChGene KnockoutPuromycin0
(0)

Bestrophin-2 Double Nickase Plasmid (h2)

sc-412345-NIC-2hGene KnockoutPuromycin0
(0)

Bestrophin-2 CRISPR/Cas9 KO Plasmid (m)

sc-431832mGene KnockoutGFP0
(0)

Bestrophin-2 HDR Plasmid (m)

sc-431832-HDRmHomology Directed RepairPuromycin0
(0)

Bestrophin-2 Double Nickase Plasmid (m)

sc-431832-NICmGene KnockoutPuromycin0
(0)

Bestrophin-2 Double Nickase Plasmid (m2)

sc-431832-NIC-2mGene KnockoutPuromycin0
(0)

Bestrophin-3 CRISPR/Cas9 KO Plasmid (h)

sc-410324hGene KnockoutGFP0
(0)

Bestrophin-3 HDR Plasmid (h)

sc-410324-HDRhHomology Directed RepairPuromycin0
(0)

Bestrophin-3 Double Nickase Plasmid (h)

sc-410324-NIChGene KnockoutPuromycin0
(0)

Bestrophin-3 Double Nickase Plasmid (h2)

sc-410324-NIC-2hGene KnockoutPuromycin0
(0)

Bestrophin-3 CRISPR/Cas9 KO Plasmid (m)

sc-436395mGene KnockoutGFP0
(0)

Bestrophin-3 HDR Plasmid (m)

sc-436395-HDRmHomology Directed RepairPuromycin0
(0)

Bestrophin-3 Double Nickase Plasmid (m)

sc-436395-NICmGene KnockoutPuromycin0
(0)

Bestrophin-3 Double Nickase Plasmid (m2)

sc-436395-NIC-2mGene KnockoutPuromycin0
(0)

Bestrophin-4 CRISPR/Cas9 KO Plasmid (h)

sc-415273hGene KnockoutGFP0
(0)

Bestrophin-4 HDR Plasmid (h)

sc-415273-HDRhHomology Directed RepairPuromycin0
(0)

Bestrophin-4 Double Nickase Plasmid (h)

sc-415273-NIChGene KnockoutPuromycin0
(0)

Bestrophin-4 Double Nickase Plasmid (h2)

sc-415273-NIC-2hGene KnockoutPuromycin0
(0)

Bestrophin CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Bestrophin CRISPR Activation Plasmid (h)

sc-404183-ACThGene ActivationPuro, Blast, Hygro0
(0)

Bestrophin CRISPR Activation Plasmid (h2)

sc-404183-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

Bestrophin Lentiviral Activation Particles (h)

sc-404183-LAChGene ActivationPuro, Blast, Hygro0
(0)

Bestrophin Lentiviral Activation Particles (h2)

sc-404183-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

Bestrophin CRISPR Activation Plasmid (m)

sc-423991-ACTmGene ActivationPuro, Blast, Hygro0
(0)

Bestrophin CRISPR Activation Plasmid (m2)

sc-423991-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

Bestrophin Lentiviral Activation Particles (m)

sc-423991-LACmGene ActivationPuro, Blast, Hygro0
(0)

Bestrophin Lentiviral Activation Particles (m2)

sc-423991-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

Bestrophin-2 CRISPR Activation Plasmid (h)

sc-412345-ACThGene ActivationPuro, Blast, Hygro0
(0)

Bestrophin-2 CRISPR Activation Plasmid (h2)

sc-412345-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

Bestrophin-2 Lentiviral Activation Particles (h)

sc-412345-LAChGene ActivationPuro, Blast, Hygro0
(0)

Bestrophin-2 Lentiviral Activation Particles (h2)

sc-412345-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

Bestrophin-2 CRISPR Activation Plasmid (m)

sc-431832-ACTmGene ActivationPuro, Blast, Hygro0
(0)

Bestrophin-2 CRISPR Activation Plasmid (m2)

sc-431832-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

Bestrophin-2 Lentiviral Activation Particles (m)

sc-431832-LACmGene ActivationPuro, Blast, Hygro0
(0)

Bestrophin-2 Lentiviral Activation Particles (m2)

sc-431832-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

Bestrophin-3 CRISPR Activation Plasmid (h)

sc-410324-ACThGene ActivationPuro, Blast, Hygro0
(0)

Bestrophin-3 CRISPR Activation Plasmid (h2)

sc-410324-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

Bestrophin-3 Lentiviral Activation Particles (h)

sc-410324-LAChGene ActivationPuro, Blast, Hygro0
(0)

Bestrophin-3 Lentiviral Activation Particles (h2)

sc-410324-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

Bestrophin-3 CRISPR Activation Plasmid (m)

sc-436395-ACTmGene ActivationPuro, Blast, Hygro0
(0)

Bestrophin-3 CRISPR Activation Plasmid (m2)

sc-436395-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

Bestrophin-3 Lentiviral Activation Particles (m)

sc-436395-LACmGene ActivationPuro, Blast, Hygro0
(0)

Bestrophin-3 Lentiviral Activation Particles (m2)

sc-436395-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

Bestrophin-4 CRISPR Activation Plasmid (h)

sc-415273-ACThGene ActivationPuro, Blast, Hygro0
(0)

Bestrophin-4 CRISPR Activation Plasmid (h2)

sc-415273-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

Bestrophin-4 Lentiviral Activation Particles (h)

sc-415273-LAChGene ActivationPuro, Blast, Hygro0
(0)

Bestrophin-4 Lentiviral Activation Particles (h2)

sc-415273-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

Bestrophin siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Bestrophin siRNA (h)

sc-40368hGene SilencingN/A0
(0)

Bestrophin shRNA Plasmid (h)

sc-40368-SHhGene SilencingPuromycin0
(0)

Bestrophin shRNA (h) Lentiviral Particles

sc-40368-VhGene SilencingPuromycin0
(0)

Bestrophin siRNA (m)

sc-141686mGene SilencingN/A0
(0)

Bestrophin shRNA Plasmid (m)

sc-141686-SHmGene SilencingPuromycin0
(0)

Bestrophin shRNA (m) Lentiviral Particles

sc-141686-VmGene SilencingPuromycin0
(0)

Bestrophin-2 siRNA (h)

sc-72639hGene SilencingN/A0
(0)

Bestrophin-2 shRNA Plasmid (h)

sc-72639-SHhGene SilencingPuromycin0
(0)

Bestrophin-2 shRNA (h) Lentiviral Particles

sc-72639-VhGene SilencingPuromycin0
(0)

Bestrophin-2 siRNA (m)

sc-72640mGene SilencingN/A0
(0)

Bestrophin-2 shRNA Plasmid (m)

sc-72640-SHmGene SilencingPuromycin0
(0)

Bestrophin-2 shRNA (m) Lentiviral Particles

sc-72640-VmGene SilencingPuromycin0
(0)

Bestrophin-3 siRNA (h)

sc-72641hGene SilencingN/A0
(0)

Bestrophin-3 shRNA Plasmid (h)

sc-72641-SHhGene SilencingPuromycin0
(0)

Bestrophin-3 shRNA (h) Lentiviral Particles

sc-72641-VhGene SilencingPuromycin0
(0)

Bestrophin-3 siRNA (m)

sc-72642mGene SilencingN/A0
(0)

Bestrophin-3 shRNA Plasmid (m)

sc-72642-SHmGene SilencingPuromycin0
(0)

Bestrophin-3 shRNA (m) Lentiviral Particles

sc-72642-VmGene SilencingPuromycin0
(0)

Bestrophin-4 siRNA (h)

sc-72643hGene SilencingN/A0
(0)

Bestrophin-4 shRNA Plasmid (h)

sc-72643-SHhGene SilencingPuromycin0
(0)

Bestrophin-4 shRNA (h) Lentiviral Particles

sc-72643-VhGene SilencingPuromycin0
(0)