BC066028 Activators
Zfp941, a DNA-binding transcription factor predicted to regulate transcription by RNA polymerase II, is located in the nucleus, highlighting its significance in the intricate control of gene expression. The protein's predicted functions suggest a role in cis-regulatory region-specific DNA binding, emphasizing its potential involvement in orchestrating precise transcriptional regulation. The activation of Zfp941 is intricately linked to epigenetic modifications and chromatin dynamics. Various chemicals, such as Azacitidine and 5-Azacytidine, act as indirect activators by demethylating DNA, promoting Zfp941's binding to cis-regulatory regions and enhancing RNA polymerase II-specific DNA binding. HDAC inhibitors like Trichostatin A and SAHA impact histone acetylation, altering chromatin structure to facilitate Zfp941-mediated transcriptional regulation. Natural compounds like Curcumin and Betulinic Acid exert their effects through anti-inflammatory mechanisms, modulating chromatin accessibility for Zfp941 binding.
In conclusion, Zfp941 emerges as a pivotal player in the regulation of gene expression, with its activation intricately tied to epigenetic modifications and chromatin dynamics. Understanding the mechanisms underlying Zfp941 activation provides valuable insights into the complex landscape of transcriptional control in various cellular processes.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
DNA methyltransferase inhibitor impacting DNA methylation. Potential indirect activator of Zfp941 by demethylating cis-regulatory regions, promoting RNA polymerase II-specific DNA binding. Azacitidine's role involves epigenetic modifications that enhance Zfp941's access to regulatory elements, facilitating transcriptional regulation in the nucleus. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Polyphenolic compound with diverse cellular effects. Potential indirect activator of Zfp941 through its antioxidant and epigenetic modulating properties. Resveratrol's role may involve influencing RNA polymerase II-mediated transcription by altering the chromatin landscape, promoting Zfp941 binding to cis-regulatory regions and enhancing its transcriptional regulatory function in the nucleus. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
HDAC inhibitor impacting epigenetic regulation. Potential indirect activator of Zfp941 by inhibiting HDACs, leading to histone acetylation and altered chromatin structure in cis-regulatory regions. Trichostatin A's role involves epigenetic modifications that enhance Zfp941 binding to DNA, promoting transcriptional regulation by RNA polymerase II. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $133.00 $275.00 | 37 | |
HDAC inhibitor affecting chromatin remodeling. Potential indirect activator of Zfp941 by inhibiting HDACs, promoting histone acetylation, and influencing RNA polymerase II-specific DNA binding. SAHA's role involves epigenetic modifications that enhance Zfp941 binding to cis-regulatory regions, facilitating its transcriptional regulatory function in the nucleus. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Natural polyphenol affecting multiple signaling pathways. Potential indirect activator of Zfp941 through its anti-inflammatory and epigenetic modulation, influencing the transcriptional regulation by RNA polymerase II. Curcumin's role may involve suppressing inflammatory pathways and modifying chromatin accessibility, enhancing Zfp941 activity in the nucleus. | ||||||
(±)-JQ1 | 1268524-69-1 | sc-472932 sc-472932A | 5 mg 25 mg | $231.00 $863.00 | 1 | |
BET bromodomain inhibitor impacting gene transcription. Potential indirect activator of Zfp941 by inhibiting bromodomain proteins, altering chromatin structure, and influencing RNA polymerase II activity. JQ1's role involves modulating the epigenetic landscape to facilitate Zfp941 binding to cis-regulatory regions and enhance its transcriptional regulatory function in the nucleus. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
HDAC inhibitor modulating gene expression. Potential indirect activator of Zfp941 by inhibiting HDACs, leading to increased histone acetylation and altered chromatin accessibility for RNA polymerase II. Sodium Butyrate's role involves epigenetic modifications that enhance Zfp941 binding to cis-regulatory regions, promoting transcriptional regulation in the nucleus. | ||||||
Betulinic Acid | 472-15-1 | sc-200132 sc-200132A | 25 mg 100 mg | $117.00 $344.00 | 3 | |
Natural triterpenoid impacting multiple pathways. Potential indirect activator of Zfp941 through its anti-inflammatory and epigenetic modulating properties. Betulinic Acid's role involves influencing RNA polymerase II-mediated transcription by modifying chromatin accessibility, promoting Zfp941 binding to cis-regulatory regions and enhancing its transcriptional regulatory function in the nucleus. | ||||||
A-485 | 1889279-16-6 | sc-507493 | 5 mg | $275.00 | ||
PARP inhibitor impacting chromatin structure. Potential indirect activator of Zfp941 through PARP inhibition, influencing RNA polymerase II-mediated transcription. A-485's role involves modulating the chromatin environment to facilitate Zfp941 binding to cis-regulatory regions and enhance its transcriptional regulatory function in the nucleus. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $218.00 $322.00 $426.00 | 7 | |
DNA methyltransferase inhibitor influencing DNA methylation. Potential indirect activator of Zfp941 by demethylating cis-regulatory regions, promoting RNA polymerase II-specific DNA binding. Decitabine's role involves epigenetic modifications that enhance Zfp941's access to regulatory elements, facilitating transcriptional regulation in the nucleus. | ||||||