Astrotactin 2 Activators
Astrotactin 2 activators are a diverse group of chemical compounds that directly or indirectly enhance the functional activity of Astrotactin 2. Retinoic Acid, a vitamin A metabolite, enhances neuronal differentiation and neurite outgrowth, processes that Astrotactin 2 is directly involved in. Similarly, N6-Cyclopentyladenosine (CPA), an adenosine receptor agonist, and Sphingosine-1-Phosphate (S1P), a bioactive lipid mediator, activate receptors that are crucial for cell migration and adhesion, thereby enhancing Astrotactin 2's functional activity. Forskolin and Rolipram, which increase the production of cAMP, and S-Nitroso-N-acetyl-DL-penicillamine (SNAP), a nitric oxide donor that increases cGMP levels, influence second messenger systems to promote cellular processes like cell adhesion and migration, thereby enhancing the functional activity of Astrotactin 2.
Bradykinin, Thrombin, Lysophosphatidic Acid (LPA), and Prostaglandin E2 (PGE2) activate various receptors that regulate cell adhesion and migration, directly enhancing the functional activity of Astrotactin 2 in these processes. Spermine, a polyamine, enhances cell growth and function, including cell adhesion and migration, thereby indirectly influencing the functional activity of Astrotactin 2. Bisindolylmaleimide I (BIM), an inhibitor of protein kinase C (PKC), modulates cell adhesion and migration through PKC inhibition, leading to enhanced functional activity of Astrotactin 2.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic acid, a vitamin A metabolite, is known to enhance neuronal differentiation and neurite outgrowth, both of which are processes Astrotactin 2 (ASTN2) is directly involved in. Increased neuronal differentiation and neurite outgrowth can lead to enhanced functional activity of ASTN2 in neuronal migration. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin directly activates adenylyl cyclase, leading to increased production of cAMP. This second messenger is known to enhance cell adhesion and migration, processes that ASTN2 is directly involved in. This can lead to an increase in ASTN2's functional activity. | ||||||
D-erythro-Sphingosine-1-phosphate | 26993-30-6 | sc-201383 sc-201383D sc-201383A sc-201383B sc-201383C | 1 mg 2 mg 5 mg 10 mg 25 mg | $165.00 $322.00 $570.00 $907.00 $1727.00 | 7 | |
S1P activates S1P receptors that are directly involved in cell migration and adhesion. ASTN2, also being involved in these processes, can have its functional activity enhanced by S1P. | ||||||
Rolipram | 61413-54-5 | sc-3563 sc-3563A | 5 mg 50 mg | $77.00 $216.00 | 18 | |
Rolipram, a selective phosphodiesterase 4 inhibitor, increases cAMP levels. As cAMP is known to enhance cell adhesion and migration, processes that ASTN2 is directly involved in, this can lead to increased functional activity of ASTN2. | ||||||
Thrombin from human plasma | 9002-04-4 | sc-471713 | 100 U | $235.00 | ||
Thrombin activates protease-activated receptors (PARs), which can modulate cell adhesion and migration, processes that ASTN2 is directly related to. This activation can enhance the functional activity of ASTN2. | ||||||
(±)-S-Nitroso-N-acetylpenicillamine | 79032-48-7 | sc-200319B sc-200319 sc-200319A | 10 mg 20 mg 100 mg | $74.00 $114.00 $374.00 | 18 | |
SNAP, a nitric oxide donor, activates guanylate cyclase, leading to increased cGMP levels. cGMP is known to participate in cell adhesion and migration, thereby enhancing the functional activity of ASTN2 in these processes. | ||||||
Lysophosphatidic Acid | 325465-93-8 | sc-201053 sc-201053A | 5 mg 25 mg | $98.00 $341.00 | 50 | |
LPA activates LPA receptors, which are known to be involved in cell adhesion and migration. This activation can enhance the functional activity of ASTN2 in neuronal migration. | ||||||
PGE2 | 363-24-6 | sc-201225 sc-201225C sc-201225A sc-201225B | 1 mg 5 mg 10 mg 50 mg | $57.00 $159.00 $275.00 $678.00 | 37 | |
PGE2 activates PGE2 receptors, which are known to participate in cell adhesion and migration. This can directly enhance the functional activity of ASTN2 in these processes. | ||||||
Spermine | 71-44-3 | sc-212953A sc-212953 sc-212953B sc-212953C | 1 g 5 g 25 g 100 g | $61.00 $196.00 $277.00 $901.00 | 1 | |
Spermine, a polyamine, is known to influence cell growth and function, including cell adhesion and migration. These processes are directly related to the functional activity of ASTN2, and thus spermine can enhance ASTN2's functional activity. | ||||||
Bisindolylmaleimide I (GF 109203X) | 133052-90-1 | sc-24003A sc-24003 | 1 mg 5 mg | $105.00 $242.00 | 36 | |
BIM, an inhibitor of protein kinase C (PKC), can influence cell adhesion and migration, processes that ASTN2 is directly involved in. By inhibiting PKC, BIM can lead to increased functional activity of ASTN2. | ||||||