ARRDC3 inhibitors are not well-established. However, the chemicals listed above represent a spectrum of inhibitors that target various signaling pathways and cellular processes, potentially influencing ARRDC3 activity indirectly. These inhibitors are primarily focused on pathways like PI3K, MAPK/ERK, mTOR, NF-κB, and various kinases. The inhibition of these pathways can lead to altered cellular processes, potentially impacting the function and regulation of proteins like ARRDC3.
For instance, inhibitors of the PI3K and MAPK/ERK pathways, such as Wortmannin and U0126, can disrupt signal transduction processes critical for cell growth, survival, and differentiation. By modulating these pathways, it's possible to influence the activity or expression of proteins indirectly associated with these pathways, like ARRDC3. For instance, inhibitors of the PI3K and MAPK/ERK pathways, such as Wortmannin and U0126, can disrupt signal transduction processes critical for cell growth, survival, and differentiation. By modulating these pathways, it's possible to influence the activity or expression of proteins indirectly associated with these pathways, like ARRDC3. Similarly, inhibitors targeting the mTOR pathway (e.g., Rapamycin) or the NF-κB pathway (e.g., BAY 11-7082) can affect cellular processes like growth, proliferation, and inflammation. These broad effects might alter the cellular environment in a way that influences ARRDC3.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
A potent inhibitor of phosphoinositide 3-kinases (PI3K), which can affect endocytosis and signaling pathways potentially linked to ARRDC3. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
Another PI3K inhibitor, it may alter cellular processes including those associated with ARRDC3 function. | ||||||
Dynamin Inhibitor I, Dynasore | 304448-55-3 | sc-202592 | 10 mg | $89.00 | 44 | |
A dynamin inhibitor, impacts clathrin-mediated endocytosis, a process in which ARRDC3 could be involved. | ||||||
Pitstop 2 | 1419320-73-2 | sc-507418 | 10 mg | $360.00 | ||
Inhibits clathrin-dependent endocytosis, potentially affecting processes involving ARRDC3. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
A tyrosine kinase inhibitor that might indirectly affect ARRDC3-related signaling pathways. | ||||||
PP 2 | 172889-27-9 | sc-202769 sc-202769A | 1 mg 5 mg | $94.00 $227.00 | 30 | |
An Src family kinase inhibitor, potentially impacting signaling pathways associated with ARRDC3. | ||||||
MRT67307 | 1190378-57-4 | sc-507433 | 10 mg | $234.00 | ||
Inhibits TBK1 and IKKε, kinases that could be linked to pathways involving ARRDC3. | ||||||
BX 795 | 702675-74-9 | sc-281689 sc-281689A sc-281689C sc-281689B sc-281689D sc-281689E | 2 mg 5 mg 10 mg 25 mg 50 mg 100 mg | $219.00 $273.00 $331.00 $495.00 $882.00 $1489.00 | 5 | |
A TBK1 inhibitor, potentially affecting signaling pathways related to ARRDC3. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
An MEK inhibitor, may influence pathways that intersect with ARRDC3 functions. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
A JNK inhibitor, which may affect signaling pathways involving ARRDC3. | ||||||