Date published: 2025-12-18

1-800-457-3801

SCBT Portrait Logo
Seach Input

ARF Inhibitors

Santa Cruz Biotechnology now offers a broad range of ARF Inhibitors for use in various applications. ARF inhibitors target ADP-ribosylation factor (ARF) proteins, which are small GTP-binding proteins that play a pivotal role in regulating various cellular processes, including vesicle formation, membrane trafficking, and actin cytoskeleton organization. These inhibitors are critical tools in scientific research, as they allow researchers to dissect the complex pathways controlled by ARF proteins, particularly in the context of intracellular transport and signal transduction. By inhibiting ARF function, scientists can study the impact of disrupted ARF signaling on cellular organization, such as the effects on Golgi apparatus structure, vesicle budding, and the dynamics of endocytosis and exocytosis. Additionally, ARF inhibitors are valuable for exploring how ARF proteins interact with other regulatory molecules, including their role in lipid metabolism and the maintenance of cell shape and motility. In cell biology, these inhibitors are used to investigate the consequences of impaired ARF activity on cellular functions, providing insights into the mechanisms underlying various physiological processes. Furthermore, ARF inhibitors are employed in studies aimed at identifying the specific roles of different ARF isoforms, helping to study the distinct and overlapping functions of these proteins in diverse cellular contexts. The availability of a wide range of ARF inhibitors enables researchers to tailor their experimental approaches to specific aspects of ARF-mediated signaling, advancing our understanding of intracellular transport mechanisms and the regulation of cellular architecture. View detailed information on our available ARF Inhibitors by clicking on the product name.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Brefeldin A

20350-15-6sc-200861C
sc-200861
sc-200861A
sc-200861B
1 mg
5 mg
25 mg
100 mg
$30.00
$52.00
$122.00
$367.00
25
(3)

Brefeldin A functions as a potent ARF by disrupting the Golgi apparatus and endoplasmic reticulum dynamics. It specifically inhibits the guanine nucleotide exchange factor (GEF) activity, leading to the inactivation of ARF proteins. This compound alters membrane trafficking by preventing the recruitment of coat proteins, thereby affecting vesicle formation. Its unique ability to induce organelle fusion highlights its role in modulating intracellular transport mechanisms.

ARF inhibitor

sc-3030
0.5 mg
$95.00
1
(0)

ARF inhibitors are characterized by their ability to modulate the activity of ADP-ribosylation factors, impacting cellular signaling pathways. These compounds interact with specific protein domains, altering the conformational state of ARF proteins. By inhibiting GTP binding, they disrupt the activation cycle of ARF, leading to changes in cytoskeletal dynamics and membrane organization. Their influence on vesicle budding and transport processes underscores their role in cellular homeostasis.

ARF Inhibitory Peptide (P-13)

sc-200866
1 mg
$127.00
(0)

ARF Inhibitory Peptide (P-13) functions by selectively disrupting the interaction between ARF proteins and their downstream effectors. This peptide binds to the ARF GTPase, preventing its activation and subsequent signaling cascades. By interfering with the nucleotide exchange process, P-13 alters the dynamics of membrane trafficking and cytoskeletal rearrangements. Its unique ability to modulate protein-protein interactions highlights its significance in regulating cellular architecture and function.