ARF inhibitor

The ARF inhibitor, a compound designed to target the ADP-ribosylation factor (ARF) protein family, has garnered significant attention in scientific research for its pivotal role in elucidating intracellular trafficking processes and membrane dynamics. ARF proteins, small GTPases, regulate various cellular functions, including vesicle budding, membrane trafficking, and cytoskeletal organization. By inhibiting ARF activity, ARF inhibitors interfere with these cellular processes, offering insights into the molecular mechanisms underlying intracellular trafficking pathways. Research utilizing ARF inhibitors has contributed to the understanding of vesicular transport between organelles, such as the endoplasmic reticulum and Golgi apparatus, and the plasma membrane. Additionally, ARF inhibitors have been instrumental in studying the involvement of ARF proteins in diseases like cancer, neurodegenerative disorders, and infectious diseases. By elucidating the complex mechanisms of ARF protein regulation and its impact on cellular physiology and pathology, ARF inhibitors continue to serve as valuable tools in basic and translational research aimed at identifying novel targets and developing strategies to modulate cellular trafficking pathways.