ARF Inhibitory Peptide (P-13) MF: C85H131N21O21 xC2HF3O2
MW: 1782
An ARF activity Inhibitor.

ARF Inhibitory Peptide (P-13)

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Synonym: GNIFANLFKGLFGKKE
Application: An ARF activity Inhibitor
Purity: 97%
Molecular Weight: 1782
Molecular Formula: C85H131N21O21 xC2HF3O2
* Refer to Certificate of Analysis for lot specific data (including water content).
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ARF Inhibitory Peptide (P-13) has shown to have a number of inhibitory effects. Through inhibition of ARF activity the peptide can block the secretion of proteins through inhibition of transport from endoplasmic reticulum to the Golgi apparatus and intra-Golgi transport. ARF Inhibitory Peptide (P-13) can also block endosome fusion in vitro as well as display inhibitory effects on cholera toxin.


References

1. Kahn, R.A., et al. 1992. J. Biol. Chem. 267: 13039-13046. PMID: 1618801
2. Lenhard, J.M., et al. 1992. J. Biol. Chem. 267: 13047-13052. PMID: 1618802
3. Balch, W.E., et al. 1992. J. Biol. Chem. 267: 13053-13061. PMID: 1618803
4. Randazzo, P.A., et al. 1993. J. Biol. Chem. 268: 9555-9563. PMID: 8486645

Formulation :
Supplied as trifluoroacetate salt
Physical State :
Solid
Sequence :
Gly-Asn-Ile-Phe-Ala-Asn-Leu-Phe-Lys-Gly-Leu-Phe-Gly- Lys-Lys-Glu
Solubility :
Soluble in water.
Storage :
Store at -20° C
IC50 :
ARF-dependent ADP-ribosylation: IC50 = 10-40 µM
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Download SDS (MSDS)

Certificate of Analysis

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