ARF Inhibitory Peptide (P-13)
Alternate Names:
GNIFANLFKGLFGKKE
Application:
ARF Inhibitory Peptide (P-13) is an ARF activity Inhibitor
Purity:
97%
Molecular Weight:
1782
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
ARF Inhibitory Peptide (P-13) has shown to have a number of inhibitory effects. Through inhibition of ARF activity the peptide can block the secretion of proteins through inhibition of trasnport from endoplasmic reticulum to the Golgi apparatus and intra-Golgi transport. ARF Inhibitory Peptide (P-13) can also block endosome fusion in vitro as well as display inhibitory effects on cholera toxin.
ARF Inhibitory Peptide (P-13) References
- The amino terminus of ADP-ribosylation factor (ARF) is a critical determinant of ARF activities and is a potent and specific inhibitor of protein transport. | Kahn, RA., et al. 1992. J Biol Chem. 267: 13039-46. PMID: 1618801
- Evidence for ADP-ribosylation factor (ARF) as a regulator of in vitro endosome-endosome fusion. | Lenhard, JM., et al. 1992. J Biol Chem. 267: 13047-52. PMID: 1618802
- ADP-ribosylation factor is required for vesicular trafficking between the endoplasmic reticulum and the cis-Golgi compartment. | Balch, WE., et al. 1992. J Biol Chem. 267: 13053-61. PMID: 1618803
- Activation of ADP-ribosylation factor by Golgi membranes. Evidence for a brefeldin A- and protease-sensitive activating factor on Golgi membranes. | Randazzo, PA., et al. 1993. J Biol Chem. 268: 9555-63. PMID: 8486645
Inhibitor of:
ARF.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ARF Inhibitory Peptide (P-13), 1 mg | sc-200866 | 1 mg | $127.00 |