Apoptosis Inducers
Items 131 to 134 of 134 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
SU 9516 | 377090-84-1 | sc-222330 sc-222330A | 5 mg 25 mg | $122.00 $383.00 | 3 | |
SU 9516 functions as a potent apoptosis inducer by selectively targeting mitochondrial pathways. It enhances the release of cytochrome c, which activates the intrinsic apoptotic cascade. This compound also modulates Bcl-2 family proteins, tipping the balance towards pro-apoptotic members. Its unique interaction with cellular membranes facilitates the formation of reactive oxygen species, further driving the apoptotic process. The compound exhibits a rapid engagement with cellular targets, underscoring its dynamic role in apoptosis regulation. | ||||||
BX-912 | 702674-56-4 | sc-364451 sc-364451A | 2 mg 5 mg | $124.00 $260.00 | 1 | |
BX-912 acts as a powerful apoptosis inducer by disrupting key signaling pathways within the cell. It specifically inhibits the activity of certain kinases, leading to the activation of stress response mechanisms that promote cell death. This compound also influences the phosphorylation status of various proteins, altering their interactions and stability. Its ability to generate reactive oxygen species enhances cellular stress, pushing cells towards apoptosis through a cascade of molecular events. | ||||||
Sodium dichloroacetate | 2156-56-1 | sc-203275 sc-203275A | 10 g 50 g | $54.00 $205.00 | 6 | |
Sodium dichloroacetate functions as an apoptosis inducer by modulating metabolic pathways, particularly by inhibiting pyruvate dehydrogenase kinase. This inhibition leads to increased pyruvate oxidation and a shift in cellular energy metabolism, promoting oxidative stress. The compound also influences mitochondrial dynamics, enhancing the release of pro-apoptotic factors. Its unique ability to alter cellular redox states and metabolic flux contributes to the initiation of programmed cell death. | ||||||
Gambogic Acid | 2752-65-0 | sc-200137 sc-200137A sc-200137B sc-200137C sc-200137D | 5 mg 25 mg 100 mg 500 mg 1 g | $85.00 $243.00 $419.00 $720.00 $1230.00 | 5 | |
Gambogic Acid acts as an apoptosis inducer through its interaction with various signaling pathways, particularly by activating caspases and promoting the release of cytochrome c from mitochondria. This compound disrupts the balance of pro- and anti-apoptotic proteins, leading to mitochondrial membrane permeabilization. Additionally, it enhances reactive oxygen species production, further driving the apoptotic process by inducing cellular stress responses and DNA damage. | ||||||