alpha2B-AR Inhibitors
Items 11 to 14 of 14 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Imiloxan Hydrochloride | 81167-22-8 | sc-224023 sc-224023A | 10 mg 50 mg | $215.00 $866.00 | ||
Imiloxan Hydrochloride functions as a selective alpha2B-adrenergic receptor antagonist, showcasing unique interaction patterns that stabilize receptor conformations. Its binding involves intricate electrostatic and van der Waals forces, which modulate receptor activity and influence intracellular signaling. The compound exhibits a distinctive kinetic behavior, allowing for precise alterations in adrenergic transmission, thereby affecting various physiological processes and regulatory networks. | ||||||
SKF-86466 hydrochloride | 86129-54-6 | sc-253566 | 10 mg | $133.00 | ||
SKF-86466 hydrochloride acts as a selective antagonist for the alpha2B-adrenergic receptor, characterized by its ability to disrupt receptor-ligand interactions through specific hydrogen bonding and hydrophobic contacts. This compound influences downstream signaling pathways by altering G-protein coupling dynamics, leading to nuanced changes in neurotransmitter release. Its unique structural features contribute to a distinct pharmacokinetic profile, enhancing its interaction specificity within adrenergic systems. | ||||||
Prazosin | 19216-56-9 | sc-280021 | 1 mg | $108.00 | 9 | |
Prazosin functions as an antagonist at the alpha2B-adrenergic receptor, exhibiting unique binding characteristics that involve intricate electrostatic interactions and steric hindrance. This compound modulates receptor conformation, impacting the activation of intracellular signaling cascades. Its distinct molecular architecture facilitates selective engagement with adrenergic pathways, influencing receptor desensitization and internalization processes, thereby altering cellular responses in a targeted manner. | ||||||
Prazosin-d8 | 1006717-55-0 | sc-219639 | 1 mg | $500.00 | ||
Prazosin-d8 acts as a selective antagonist at the alpha2B-adrenergic receptor, characterized by its deuterated structure that enhances stability and alters kinetic properties. The presence of deuterium modifies hydrogen bonding dynamics, potentially influencing receptor affinity and selectivity. This compound's unique isotopic composition may also affect metabolic pathways, leading to distinct pharmacokinetic profiles and interactions with downstream signaling molecules, thereby fine-tuning cellular responses. | ||||||