Prazosin CAS: 19216-56-9
MF: C19H21N5O4
MW: 383.41
A useful α1 and α2B-adrenoceptor antagonist.

Prazosin (CAS 19216-56-9)

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getAggregateRating, 108ms
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
Application: Prazosin is a useful α1 and α2B-adrenoceptor antagonist
CAS Number: 19216-56-9
Molecular Weight: 383.41
Molecular Formula: C19H21N5O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

Prazosin is an adrenergic α, α2B-adrenoceptor and a potent melatonin MT3 receptor antagonist. A study investigated the putative inhibitory effect of prazosin on changes evoked by a NMDA receptor antagonist, MK-801 within the Syrian hamster hypothalamus in vitro. This study reported that prazosin was a potent and selective α1-adrenoceptor antagonist and was able to supress MK-801 evoked changes, without affecting basal dopamine release in nucleus accumbens in vitro. Additionally, in this study prazosin was reported to block MK-801 evoked locomotor stimulation with little affect on basal locomotor activity in vitro.
Also offered as a salt: Prazosin hydrochloride (sc-204858.)


1. Pickering, D.S. and Niles, L.P. 1990. Eur. J. Pharmacol. 175: 71-77. PMID: 2157597
2. Mathé, J.M., et al. 1996. Eur. J. Pharmacol. 309: 1-11. PMID: 8864686
3. Paul, P., et al. 1999. J. Pharmacol. Exp. Ther. 290: 334-340. PMID: 10381796

Physical State :
Storage :
Store at room temperature
Melting Point :
279-285° C
Boiling Point :
638.4° C at 760 mmHg
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :

Download SDS (MSDS)

Certificate of Analysis

Adobe Acrobat Reader is required to reliably view,
print and comment on PDF documents

Prazosin (CAS 19216-56-9)  Product Citations

See how others have used Prazosin (CAS 19216-56-9). Click on the entry to view the PubMed entry .

Citations 1 to 3 of 3 total

PMID: # 31111492  Yue, L.|Qin, X.|Liu, X.|Wang, Z.|Dong, Y.|Chen, Y.|Cao, J.| et al. 2019. Photochem. Photobiol.

PMID: # 28660299  Guo, Q.|Wang, Z.|Dong, Y.|Cao, J.|Chen, Y.| et al. 2017. Cell Tissue Res. 369: 555-565.

PMID: # 27128575  Li, S.|Cao, J.|Wang, Z.|Dong, Y.|Wang, W.|Chen, Y.| et al. 2016. Photochem. Photobiol. 92: 595-603.

Citations 1 to 3 of 3 total

Is this product soluble in DMSO?

Asked by: hawkeye11
Thank you for your question. Prazosin, sc-280021, is soluble in DMSO. Please follow this linked protocol:
Answered by: TechService7
Date published: 2018-07-06
  • y_2020, m_9, d_30, h_15CST
  • bvseo_bulk, prod_bvqa, vn_bulk_3.0.12
  • cp_1, bvpage1
  • co_hasquestionsanswers, tq_1
  • loc_en_US, sid_280021, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 126ms
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 9ms
  • bvseo-msg: The resource to the URL or file is currently unavailable.;

Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2020 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.