alpha1B-AR Inhibitors
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Carvedilol | 72956-09-3 | sc-200157 sc-200157A sc-200157B sc-200157C sc-200157D | 100 mg 1 g 10 g 25 g 100 g | $122.00 $235.00 $520.00 $979.00 $1500.00 | 2 | |
Carvedilol functions as an alpha1B-adrenergic receptor antagonist, characterized by its dual action on both alpha and beta receptors. Its unique structure allows for selective binding, where specific hydrophobic pockets facilitate strong interactions. The compound's conformational flexibility enhances its ability to modulate receptor activity, while its lipophilicity influences membrane permeability and distribution. Additionally, carvedilol's kinetic profile reveals a complex interplay of binding and dissociation rates, impacting its overall pharmacodynamics. | ||||||
Benoxathian hydrochloride | 92642-97-2 | sc-254954 | 10 mg | $90.00 | ||
Benoxathian hydrochloride acts as an alpha1B-adrenergic receptor antagonist, exhibiting a distinctive binding affinity due to its unique molecular architecture. The compound's specific interactions with receptor sites involve hydrogen bonding and hydrophobic interactions, which stabilize its conformation. Its dynamic behavior in solution suggests rapid equilibrium between bound and unbound states, influencing its efficacy in receptor modulation. Furthermore, the compound's solubility characteristics enhance its distribution in biological systems, affecting its interaction kinetics. | ||||||
Spiperone hydrochloride | 2022-29-9 | sc-204293 | 50 mg | $173.00 | ||
Spiperone hydrochloride functions as an alpha1B-adrenergic receptor antagonist, characterized by its intricate molecular structure that facilitates selective receptor binding. The compound engages in specific electrostatic interactions and π-π stacking with aromatic residues, enhancing its affinity. Its kinetic profile indicates a notable rate of association and dissociation, allowing for nuanced modulation of receptor activity. Additionally, its lipophilicity influences membrane permeability, impacting its overall bioavailability in various environments. | ||||||
Tamsulosin Hydrochloride | 106463-17-6 | sc-203289 sc-203289A | 10 mg 25 mg | $132.00 $260.00 | ||
Tamsulosin Hydrochloride acts as an alpha1B-adrenergic receptor antagonist, distinguished by its unique stereochemistry that promotes selective binding. The compound exhibits strong hydrogen bonding and hydrophobic interactions with receptor sites, optimizing its affinity. Its reaction kinetics reveal a rapid onset of action, with a prolonged duration due to slow dissociation rates. Furthermore, its solubility characteristics enhance its distribution in biological systems, influencing its interaction dynamics. | ||||||
Terazosin Hydrochloride dihydrate | 70024-40-7 | sc-205857 sc-205857A | 50 mg 250 mg | $112.00 $444.00 | ||
Terazosin Hydrochloride dihydrate functions as an alpha1B-adrenergic receptor antagonist, characterized by its ability to stabilize receptor conformations through specific electrostatic interactions. The compound's unique hydration state enhances its solubility, facilitating effective molecular diffusion. Its kinetic profile indicates a moderate binding affinity, with a balanced rate of association and dissociation, allowing for nuanced modulation of receptor activity. Additionally, its structural flexibility contributes to diverse interaction pathways within biological membranes. | ||||||
L-765,314 | 189349-50-6 | sc-493741 | 5 mg | $300.00 | 3 | |
L-765,314 is a selective alpha1B-adrenergic receptor antagonist known for its unique allosteric modulation capabilities. Its structural conformation enables specific interactions with the receptor's binding site, leading to altered conformational states that impact signal transduction pathways. The compound exhibits a distinctive kinetic profile, characterized by a prolonged receptor occupancy and a gradual dissociation rate, which enhances its efficacy in modulating receptor activity over time. | ||||||