Molecular structure of Spiperone hydrochloride, CAS Number: 2022-29-9
Spiperone hydrochloride (CAS 2022-29-9)
Alternate Names:
Spiroperidol Hydrochloride
Application:
Spiperone hydrochloride is a D2DR, SR-1A, and SR-2A inhibitor
CAS Number:
2022-29-9
Purity:
≥98%
Molecular Weight:
431.94
Molecular Formula:
C23H26FN3O2•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Spiperone hydrochloride is an analogue of Spiperone. Spiperone (sc-204293) is an SR-2A and selective D2DR inhibitor (Ki values are 0.06, 0.6, 0.08, ~ 350, ~ 3500 nM for D2DR, D3DR, D4DR, D1DR, and D5DR respectively). Although the well known role of Spiperone in research studies indicates it acts as an inhibitor of either SR-2 or D2DR, Spiperone has also been reported to act through a protein tyrosine kinase-coupled phospholipase CO-dependent pathway. Spiperone was observed to act independent of either SR-2 or D2DR as reported In a study investigating the role of Spiperone and Ca2+ activated Cl- (CaCC) in human cystic fibrosis (CF) airway epithelial cell monolayers in vitro. Spiperone hydrochloride is an inhibitor of alpha1B-AR.
Spiperone hydrochloride (CAS 2022-29-9) References
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Inhibitor of:
alpha1B-AR, D2DR, D3DR, D4DR, SR-2A, and SR-2C.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Spiperone hydrochloride, 50 mg | sc-204293 | 50 mg | $173.00 |