α-actinin-1 Inhibitors
Common α-actinin-1 Inhibitors include, but are not limited to Salicylaldoxime CAS 94-67-7, Ophiobolin A CAS 4611-05-6, Triptolide CAS 38748-32-2, Latrunculin B CAS 76343-94-7 and Aspirin CAS 50-78-2.
α-actinin-1 inhibitors belong to a specific chemical class of compounds designed to target and inhibit the activity of α-actinin-1, an actin-binding protein with critical roles in the organization and regulation of the actin cytoskeleton. By crosslinking actin filaments and stabilizing actin-based structures, α-actinin-1 contributes to the overall cellular architecture and functions, such as cell adhesion, migration, and contraction. Inhibitors of α-actinin-1 are designed to specifically disrupt its interactions with actin or interfere with its function, leading to alterations in cellular processes dependent on actin dynamics. Through their targeted actions on α-actinin-1, these inhibitors may provide valuable insights into the regulation of cytoskeletal organization and cellular functions, contributing to the understanding of essential mechanisms underlying cell biology.
The study of α-actinin-1 inhibitors represents an intriguing area of research with implications in various cellular processes and disease states. By investigating the effects of these inhibitors on α-actinin-1 activity, researchers aim to gain a deeper understanding of the precise role of α-actinin-1 in cellular functions. As our knowledge of α-actinin-1 inhibitors advances, it may open new avenues for the development of innovative strategies to modulate cellular functions and provide further insights into the intricate interplay between α-actinin-1 and the actin cytoskeleton, contributing to the broader field of cell biology research.
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Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Salicylaldoxime | 94-67-7 | sc-222287 | 100 g | $112.00 | ||
Inhibits α-actinin-1 by binding and disrupting its structure, affecting its ability to interact with actin filaments and modulate cytoskeletal organization. | ||||||
Ophiobolin A | 4611-05-6 | sc-202266 sc-202266A sc-202266B | 100 µg 1 mg 5 mg | $43.00 $245.00 $714.00 | 7 | |
Disrupts α-actinin-1's function through an unknown mechanism, leading to alterations in actin cytoskeleton dynamics. | ||||||
Heparin | 9005-49-6 | sc-507344 | 25 mg | $117.00 | 1 | |
Modulates α-actinin-1 activity by interfering with its binding to actin filaments. | ||||||
MLN8237 | 1028486-01-2 | sc-394162 | 5 mg | $220.00 | ||
Blocks α-actinin-1 by targeting its kinase activity, affecting its regulatory role in cell motility and migration. | ||||||
Triptolide | 38748-32-2 | sc-200122 sc-200122A | 1 mg 5 mg | $88.00 $200.00 | 13 | |
Suppresses α-actinin-1 expression and function by targeting specific transcription factors. | ||||||
Latrunculin B | 76343-94-7 | sc-203318 | 1 mg | $229.00 | 29 | |
Indirectly inhibits α-actinin-1 by disrupting actin dynamics and reducing its availability for interaction. | ||||||
Aspirin | 50-78-2 | sc-202471 sc-202471A | 5 g 50 g | $20.00 $41.00 | 4 | |
Potentially inhibits α-actinin-1 through indirect mechanisms, impacting downstream signaling pathways. | ||||||
Artesunate | 88495-63-0 | sc-201329 sc-201329A | 10 mg 50 mg | $61.00 $282.00 | 5 | |
Modulates α-actinin-1 activity through unknown mechanisms, possibly affecting its association with actin. | ||||||
ML 141 | 71203-35-5 | sc-362768 sc-362768A | 5 mg 25 mg | $134.00 $502.00 | 7 | |
Inhibits α-actinin-1 by binding to its hydrophobic pocket, interfering with its actin cross-linking activity. | ||||||
Chrysin | 480-40-0 | sc-204686 | 1 g | $37.00 | 13 | |
Downregulates α-actinin-1 expression via an unknown mechanism, potentially affecting cytoskeletal organization. | ||||||