ALK Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
VEGFR2 Kinase Inhibitor III | 204005-46-9 | sc-202851 | 5 mg | $165.00 | 7 | |
A VEGFR2 Kinase Inhibitor III compound. It functions as an inhibitor of ALK, a protein involved in cellular processes. Its molecular properties enable targeted interaction with ALK, modulating its activity. | ||||||
TAE684 | 761439-42-3 | sc-364626 sc-364626A | 5 mg 50 mg | $188.00 $988.00 | 2 | |
A powerful inhibitor of ALK. It targets NPM-ALK phosphorylation, leading to cell cycle arrest and apoptosis in Ba/F3 cell lines. Effective against Ba/F3 NPM-ALK cells. it spares general cell viability. It also restrains proliferation in NPM-ALK-expressing human ALCL cell like Karpas-299 and SU-DHL-1. | ||||||
A 77-01 | 607737-87-1 | sc-396001 | 5 mg | $194.00 | ||
Recognized for its capability to inhibit ALK5, a prominent member of the TGF-β type I receptor superfamily. A 77-01 effectively interferes with ALK5's functionality, highlighting its potential as a tool compound for modulating TGF-β signaling pathways. | ||||||
CH5424802 | 1256580-46-7 | sc-364461 sc-364461A | 5 mg 50 mg | $191.00 $902.00 | ||
A potent ALK inhibitor that competes with ATP. By inhibiting autophosphorylation, it curbs ALK activity and suppresses STAT3 and AKT phosphorylation (not ERK1/2). CH5424802 triggers apoptotic marker caspase-3/7-like activation in NCI-H2228 spheroid cells. Effective against NPM-ALK-expressing lymphoma lines KARPAS-299 and SR, it notably hinders KARPAS-299 growth. | ||||||
SB-505124 | 694433-59-5 | sc-362794 sc-362794A | 10 mg 50 mg | $327.00 $1377.00 | 2 | |
Functions as an ALK inhibitor, impeding the activity of the receptor. It operates by blocking the ALK signaling pathway, which plays a role in various cellular processes. | ||||||
GW788388 | 452342-67-5 | sc-363544 sc-363544A | 5 mg 25 mg | $95.00 $384.00 | ||
An ALK inhibitor, specifically targeting ALK5, a member of the TGF-β receptor superfamily. It effectively impedes ALK5's signaling activity, modulating cellular processes associated with this pathway. | ||||||