Molecular structure of A 77-01, CAS Number: 607737-87-1
A 77-01 (CAS 607737-87-1)
Application:
A 77-01 is an inhibitor of ALK5 with an IC50 of 25nM
CAS Number:
607737-87-1
Molecular Weight:
286.33
Molecular Formula:
C18H14N4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
A 77-01 is an inhibitor of TGF-β type I receptor superfamily activin-like kinase ALK5 with an IC50 of 25nM.
A 77-01 (CAS 607737-87-1) References
M Tojo et al. The ALK5 inhibitor A-83-01 inhibits smad signaling and epithelial-to-mesenchymal transition by transforming growth factor-β. Cancer. Sci. 2005, 96, 791-800.J Sawyer et al. Synthesis and activity of new aryl- and heteroaryl-substituted pyrazole inhibitors of the transforming growth factor-β type I receptor kinase domain. J of Medicinal Chemistry. 2003, 46, 3953-3956.
Inhibitor of:
ALK, POU3F, and TNF β.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
A 77-01, 5 mg | sc-396001 | 5 mg | $190.00 |