ALDH2 Inhibitors
Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
7-O-Ethyldaidzein | 146698-96-6 | sc-207181 | 10 mg | $380.00 | ||
7-O-Ethyldaidzein functions as an aldehyde dehydrogenase 2 (ALDH2) inhibitor, showcasing distinctive molecular interactions that modulate enzyme activity. Its structural features enable specific binding to the active site, altering the enzyme's conformation and impacting substrate turnover rates. The compound's hydrophobic regions promote interactions with lipid membranes, influencing its bioavailability and distribution. Furthermore, its reactivity profile suggests potential for diverse chemical modifications, enhancing its versatility in synthetic applications. | ||||||
Disulfiram | 97-77-8 | sc-205654 sc-205654A | 50 g 100 g | $52.00 $87.00 | 7 | |
Also known as Antabuse, disulfiram is a well-known ALDH2 inhibitor used for alcoholism. It works by inhibiting ALDH2, leading to an accumulation of acetaldehyde when alcohol is consumed, resulting in unpleasant symptoms. | ||||||
Daidzin | 552-66-9 | sc-202123 sc-202123A | 1 mg 5 mg | $71.00 $134.00 | 1 | |
Daidzin acts as a selective inhibitor of aldehyde dehydrogenase 2 (ALDH2), characterized by its unique ability to form stable complexes with the enzyme. This interaction disrupts the catalytic cycle, leading to altered reaction kinetics and substrate affinity. The compound's polar functional groups facilitate hydrogen bonding, enhancing specificity. Additionally, its lipophilic characteristics influence membrane permeability, potentially affecting cellular uptake and localization. | ||||||
7-O-w-Bromopropyldaidzein | 309252-38-8 | sc-207182 | 10 mg | $360.00 | ||
7-O-w-Bromopropyldaidzein exhibits a distinctive mechanism of action as an aldehyde dehydrogenase 2 (ALDH2) inhibitor. Its bromopropyl substituent enhances hydrophobic interactions, promoting a strong binding affinity to the enzyme's active site. This compound's unique steric configuration alters the enzyme's conformation, impacting substrate turnover rates. Furthermore, its electronic properties may influence redox reactions, contributing to its inhibitory profile and modulating metabolic pathways. | ||||||
Cyanamide | 420-04-2 | sc-239592 sc-239592A | 5 g 25 g | $21.00 $77.00 | ||
Cyanamide is an ALDH2 inhibitor that has been studied for its potential use in reducing alcohol consumption by inducing aversive reactions when alcohol is consumed. | ||||||
7-O-[2-(1,3-Dioxanyl)ethyl]daidzein | sc-217465 | 10 mg | $245.00 | |||
7-O-[2-(1,3-Dioxanyl)ethyl]daidzein functions as an aldehyde dehydrogenase 2 (ALDH2) modulator, characterized by its dioxanyl moiety that introduces unique steric and electronic effects. This compound's ability to form hydrogen bonds with key residues in the enzyme's active site enhances its binding stability. Additionally, its distinct molecular geometry may facilitate allosteric interactions, potentially altering enzyme kinetics and influencing metabolic flux in related biochemical pathways. | ||||||
Metadoxine | 74536-44-0 | sc-215305 | 25 mg | $320.00 | ||
Metadoxine is an ALDH2 inhibitor. | ||||||
Catechin | 154-23-4 | sc-205624 sc-205624A | 1 mg 5 mg | $130.00 $293.00 | 3 | |
Certain catechins found in green tea, such as epicatechin gallate, have been shown to inhibit ALDH2 activity. Green tea extracts rich in catechins have been studied for their potential protective effects against alcohol-induced liver damage. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
Quercetin is a flavonoid compound found in various fruits, vegetables, and herbs. It has been shown to inhibit ALDH2 activity. | ||||||
Acriflavine | 8048-52-0 | sc-214489 sc-214489A | 25 g 100 g | $49.00 $168.00 | 2 | |
Acriflavine is an ALDH2 inhibitor. | ||||||