ALDH1A7 Activators
Compounds such as Disulfiram, N-Acetylcysteine, and Alda-1 influence the metabolic balance of aldehydes in the cell. Disulfiram, by inhibiting aldehyde dehydrogenase enzymes, can lead to increased aldehyde levels, potentially boosting the demand for ALDH1A7 activity. N-Acetylcysteine enhances the cellular antioxidant capacity, which may indirectly increase ALDH1A7 activity by managing oxidative stress-related aldehyde accumulation. Alda-1's enhancement of ALDH2 activity can lead to a compensatory increase in ALDH1A7 activity due to interconnected metabolic pathways.
Other compounds in this class, including Omeprazole, Vitamin E, and Sulforaphane, exert their influence by modulating cellular oxidative stress and the regulation of metabolic enzymes. Omeprazole's impact on hepatic enzyme activity, Vitamin E's role as an antioxidant, and Sulforaphane's activation of the Nrf2 pathway can all indirectly enhance ALDH1A7's role in aldehyde metabolism.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
N-Acetyl-L-cysteine | 616-91-1 | sc-202232 sc-202232A sc-202232C sc-202232B | 5 g 25 g 1 kg 100 g | $34.00 $74.00 $270.00 $114.00 | 34 | |
As a precursor to glutathione, N-Acetylcysteine can enhance cellular antioxidant capacity, which may indirectly increase ALDH1A7 activity by managing oxidative stress-related aldehyde accumulation. | ||||||
Alda 1 | 349438-38-6 | sc-479867 | 50 mg | $300.00 | ||
Alda-1 enhances ALDH2 activity, another aldehyde dehydrogenase. This can lead to a compensatory increase in ALDH1A7 activity due to interconnected metabolic pathways. | ||||||
DL-α-Tocopherol | 10191-41-0 | sc-294383 sc-294383A sc-294383B sc-294383C | 5 g 25 g 100 g 500 g | $26.00 $52.00 $124.00 $326.00 | 3 | |
As an antioxidant, Vitamin E can reduce oxidative stress, potentially modulating ALDH1A7 activity in processes related to aldehyde metabolism and detoxification. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
Sulforaphane activates Nrf2, a key regulator of antioxidant response. This activation may enhance ALDH1A7 activity by upregulating pathways involved in aldehyde detoxification. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin can modulate various metabolic pathways and might enhance ALDH1A7 activity by influencing pathways involved in aldehyde metabolism. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol, through its antioxidant properties, could enhance ALDH1A7 activity by modulating oxidative stress and related aldehyde metabolism. | ||||||
Fomepizole | 7554-65-6 | sc-252838 | 1 g | $75.00 | 1 | |
Fomepizole, an inhibitor of alcohol dehydrogenase, can lead to altered aldehyde levels, potentially enhancing ALDH1A7 activity in aldehyde metabolism. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $48.00 | ||
Zinc, as a cofactor for various enzymes, may influence ALDH1A7 activity by affecting enzyme function and stability in aldehyde metabolism processes. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG, a major component of green tea, has antioxidant properties that could indirectly enhance ALDH1A7 activity in processes involving oxidative stress and aldehyde detoxification. | ||||||