AKAP 2 activators, also known as A-kinase anchoring protein 2 activators, belong to a specific class of compounds that play a pivotal role in modulating intracellular signaling pathways. A-kinase anchoring proteins (AKAPs) are a diverse family of scaffold proteins found in eukaryotic cells, and AKAP 2 is one of its prominent members. These activators are designed to interact with AKAP 2 and influence its function within the cell.
AKAP 2, or A-kinase anchoring protein 2, is a multifunctional protein that plays a crucial role in compartmentalizing intracellular signaling cascades. It acts as a molecular organizer, bringing together various signaling molecules such as protein kinase A (PKA), protein kinase C (PKC), and phosphatases in close proximity. This spatial arrangement allows for efficient and precise control of cellular processes, as different signaling components can interact and regulate each other in a coordinated manner. AKAP 2 activators are designed to enhance the interaction between AKAP 2 and its binding partners, thereby fine-tuning cellular signaling events. By doing so, these activators can impact various physiological processes, including cell growth, differentiation, and gene expression, without directly altering the levels or activities of the signaling molecules themselves.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Rolipram | 61413-54-5 | sc-3563 sc-3563A | 5 mg 50 mg | $77.00 $216.00 | 18 | |
Indirectly activates AKAP2 by increasing cAMP levels due to phosphodiesterase inhibition. | ||||||
(−)-Epinephrine | 51-43-4 | sc-205674 sc-205674A sc-205674B sc-205674C sc-205674D | 1 g 5 g 10 g 100 g 1 kg | $41.00 $104.00 $201.00 $1774.00 $16500.00 | ||
Indirectly activates AKAP2 by increasing cAMP levels through G-protein coupled receptor activation. | ||||||
Isoproterenol Hydrochloride | 51-30-9 | sc-202188 sc-202188A | 100 mg 500 mg | $28.00 $38.00 | 5 | |
Indirectly activates AKAP2 by promoting cAMP levels as a beta-adrenergic receptor agonist. | ||||||
8-Bromo-cAMP | 76939-46-3 | sc-201564 sc-201564A | 10 mg 50 mg | $126.00 $328.00 | 30 | |
Indirectly activates AKAP2 through its direct activation of PKA as a cAMP analog. | ||||||
PGE2 | 363-24-6 | sc-201225 sc-201225C sc-201225A sc-201225B | 1 mg 5 mg 10 mg 50 mg | $57.00 $159.00 $275.00 $678.00 | 37 | |
Indirectly activates AKAP2 by elevating cAMP levels via G-protein coupled receptors. | ||||||
Cilostamide (OPC 3689) | 68550-75-4 | sc-201180 sc-201180A | 5 mg 25 mg | $92.00 $357.00 | 16 | |
Indirectly activates AKAP2 by enhancing cAMP levels through phosphodiesterase inhibition. | ||||||
Papaverine | 58-74-2 | sc-279951 sc-279951A sc-279951B | 10 mg 50 mg 100 mg | $153.00 $265.00 $459.00 | ||
Indirectly activates AKAP2 by raising cAMP levels due to its phosphodiesterase inhibitory action. | ||||||