The chemical class of ADH5 Activators comprises various compounds that indirectly enhance the activity of Alcohol Dehydrogenase 5. This enzyme, pivotal in ethanol and aldehyde metabolism, plays a significant role in detoxifying harmful substances in the liver. The activators in this class function primarily by augmenting the cellular environment, cofactor availability, or indirectly influencing pathways that regulate ADH5's expression or activity. Key components such as NAD+, Zinc, and Magnesium Sulfate serve as essential cofactors, ensuring the optimal enzymatic function of ADH5. Their supplementation can directly impact the enzyme's catalytic efficiency.
In addition to these cofactors, trace elements like Molybdenum and Selenium, along with vitamins B1, B3, B5, and Folic Acid, contribute to this class by influencing metabolic pathways that intersect with ADH5's role in alcohol metabolism. These nutrients, by supporting various aspects of cellular metabolism, can indirectly enhance ADH5 activity. Alpha-Lipoic Acid, known for its antioxidant properties, and compounds like Choline and Betaine, involved in lipid metabolism and liver function, also play significant roles. Their impact on cellular redox states and metabolic pathways provides a conducive environment for the efficient functioning of ADH5.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
NAD+, Free Acid | 53-84-9 | sc-208084B sc-208084 sc-208084A sc-208084C sc-208084D sc-208084E sc-208084F | 1 g 5 g 10 g 25 g 100 g 1 kg 5 kg | $57.00 $191.00 $302.00 $450.00 $1800.00 $3570.00 $10710.00 | 4 | |
As a cofactor for ADH5, increased levels of NAD+ can enhance the enzyme's activity by providing necessary cofactors for its catalytic function. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $48.00 | ||
Zinc is a crucial cofactor for many alcohol dehydrogenases; supplementing it might enhance ADH5 activity. | ||||||
Magnesium sulfate anhydrous | 7487-88-9 | sc-211764 sc-211764A sc-211764B sc-211764C sc-211764D | 500 g 1 kg 2.5 kg 5 kg 10 kg | $46.00 $69.00 $163.00 $245.00 $418.00 | 3 | |
Magnesium ions are important cofactors for various enzymes; their presence can support the optimal activity of ADH5. | ||||||
Vitamin B1 | 59-43-8 | sc-338735 | 5 g | $611.00 | ||
Essential for carbohydrate metabolism, thiamine could indirectly influence ADH5 activity by affecting metabolic pathways. | ||||||
Nicotinic Acid | 59-67-6 | sc-205768 sc-205768A | 250 g 500 g | $62.00 $124.00 | 1 | |
Involved in NAD+ synthesis; higher niacin levels can enhance NAD+ availability, potentially boosting ADH5 activity. | ||||||
α-Lipoic Acid | 1077-28-7 | sc-202032 sc-202032A sc-202032B sc-202032C sc-202032D | 5 g 10 g 250 g 500 g 1 kg | $69.00 $122.00 $212.00 $380.00 $716.00 | 3 | |
An antioxidant that can affect cellular redox states, potentially influencing ADH5 activity. | ||||||
Selenium | 7782-49-2 | sc-250973 | 50 g | $62.00 | 1 | |
An essential trace element that can influence various metabolic pathways, potentially impacting ADH5 activity. | ||||||
Choline chloride | 67-48-1 | sc-207430 sc-207430A sc-207430B | 10 mg 5 g 50 g | $33.00 $37.00 $52.00 | 1 | |
Involved in lipid metabolism, choline can indirectly influence ADH5 activity by modulating metabolic pathways. | ||||||
Betaine | 107-43-7 | sc-214595 sc-214595A sc-214595B sc-214595C sc-214595D sc-214595E | 50 g 100 g 250 g 1 kg 2.5 kg 5 kg | $31.00 $41.00 $56.00 $163.00 $337.00 $592.00 | 2 | |
As an osmolyte and methyl donor, it can influence liver function and metabolism, potentially impacting ADH5. | ||||||
Folic Acid | 59-30-3 | sc-204758 | 10 g | $73.00 | 2 | |
Involved in one-carbon metabolism, folic acid could indirectly affect ADH5 activity through metabolic pathways. | ||||||